中药复方逆转胃癌前病变的临床研究

目的探讨中药复方对胃癌前期病变（PLGC）的逆转作用。方法将200例符合慢性萎缩性胃炎（CAG）伴肠上皮化生（Im）和（或）异型增生（Dys）诊断标准的病人随机分为中药治疗组（100例）和胃复春对照组（100例）,3个月为一个疗程,治疗2个疗程后对临床症状、胃镜及病理结果、幽门螺旋杆菌（Hp）检验结果进行比较。结果治疗后治疗组临床疗效、胃镜及病理（CAG、Im、Dys）结果、Hp检验结果与对照组比较,差异有显著性（χ2=5.308~9.072,P〈0.05）。结论中药复方是逆转PLGC的有效方剂。

CLINICAL STUDY OF TRADITIONAL CHINESE MEDICINE REVERSING GASTRIC PRECANCEROUS LESIONS

Objective To study the reverse effect of traditional Chinese medicine on precancerous lesions of gastric cancer（PLGC）. Methods This study consisted of 200 patients who met the diagnostic criteria of chronic atrophic gastritis（CAG） accompanied with intestinal metaplasia（IM） and/or dysplasia（Dys） were evenly randomized to traditional Chinese medicine treatment（TCMT） group and Weifuchun control group.A course of therapy was three months.After two courses of treatment,the clinical symptoms,gastroscopic and pathological findings,and helicobacter pylori（Hp） were analyzed and compared between the two groups. Results After treatment,the differences of clinical therapeutic efficacy,gastroscopy,pathology（CAG,IM and Dys）,and Hp between the treatment group and control group were statistically significant（χ2=5.308-9.072,P〈0.05）. Conclusion Compound recipe of traditional Chinese medicine is effective in reversing PLGC.