重度颅脑损伤后病人肠内外营养的比较

目的探讨重度颅脑损伤病人肠内外营养结合的临床应用意义及合理性。方法危重颅脑损伤病人56例,随机分为2组,观察组29例,行肠内营养（EN）和肠外营养（PN）结合支持14 d;对照组27例,行全肠外营养（TPN）支持14 d。于治疗1、7、14 d检测并比较两组血清总蛋白、清蛋白、血红蛋白、淋巴细胞计数及并发症发生率。结果治疗14 d时观察组血清总蛋白、清蛋白、血糖、血红蛋白及外周血淋巴细胞总数均高于对照组,差异有显著性（t=5.068~87.655,P〈0.05）。观察组并发症发生率低于对照组（P=0.04）。结论重度颅脑损伤EN和PN结合应用,可以明显改善病人的营养状况,提高重度颅脑损伤病人治愈率、生存率。

COMPARISON BETWEEN ENTERAL AND PARENTERAL NUTRITION IN PATIENTS WITH SEVERE CRANIOCEREBRAL INJURY

Objective To study the clinical application of combination of enteral and parenteral nutrition in patients with severe craniocerebral injury（SCCI）.Methods Fifty-six SCCI patients were divided into two groups in random： study group（enteral plus parenteral nutrition,29 cases）;control group（parenteral nutrition,27）.The course of therapy was 14 days for both groups.The levels of total serum protein,albumin,hemoglobin,lymphocytes were detected and the incidence of complications recorded on days 1,7,and 14 of therapy,respectively.Results On day 14 of treatment,the levels of total serum protein,albumin,glucose,hemoglobin,lymphocyte count in the study group were higher than that in the control（t=5.068-87.655,P0.05）,and the incidence of complications was lower（P=0.04）.Conclusion For patients with severe craniocerebral injury,combined enteral and parenteral nutrition can obviously improve their nutritional status,increase their recovery and survival rates.