视动错觉诱发的运动病动态发生过程与胃电的联系

目的 在视动刺激诱发运动病过程中，探讨胃电的变化与运动病恶心症状动态发生过程的联系，为运动病的预测和防护提供思路和依据。方法 20名18－25岁的健康男性，分别接受15min的单纯视动刺激实验，记录了运动病症状并采集了胃电信号。结果 （1）11名恶心发生者运动病分值明显高于9名恶心未发生者（P＜0．001）；同时，恶心发生者胃节律过速百分比的增加和主导慢波百分比的减少都明显大于9名恶心未发生者胃电两参数的变化（都为P＜0．001）；（2）11名恶心发生者自身旋转错觉出现的时间明显早于胃电的变化（P＜0．001）；（3）刺激过程中，11名恶心发生者胃电主导慢波（Primary Wave,Pw)和胃节律过速（Tachygastria,Tach)百分比减低或增加都明显早于恶心症状的发生（都为P＜0．01）。结论 （1）恶心时胃电的变化程度明显高于未恶心时；（2）自身旋转错觉与胃电的变化和恶心的发生有密切的关系；（3）胃电的变化先于恶心症状的出现。

Relationship Between EGG and the Dynamic Process of Motion Sickness Induced by Optokinetic Vection

Objective: To investigate the correlation between Electrogastrography (EGG) and the occurrence of nausea or/and vomit as well as the development of motion sickness (MS) induced by optokinetic stimulation (OPS) and to provide a clue and method for prediction and prevention of MS. Method: Twenty male subjects, aged from 18 to 25 years, performed the test only once with the optokinetic drum rotated around a vertical axis at the speed of 60 degrees/s for 15 min. Nausea and EGG signals were observed and recorded. Result: (1)Both the increment of tachygastric percentage and the decrement of primary wave percentage of EGG in eleven subjects with nausea were significantly larger than those in nine subjects with no nausea (both P < 0.001). (2)The circular vection preceded the changes of EGG in eleven subjects with nausea while the MS scores in eleven subjects with nausea were higher than those in nine subjects with no nausea (P < 0.001). (3)During the rotation of drum, the decrement of primary wave percentage or the increment of tachygastria percentage also preceded the occurrence of nausea in eleven subjects with nausea (both P < 0.01). Conclusion: (l)The changes of EGG in subjects with nausea were significantly greater than those of EGG in subjects with no nausea. (2)There was a close relationship between circular vection or illusory self-rotation and EGG changes as well as the occurring of nausea induced by OPS. (3)Changes of EGG preceded the nausea of MS induced by OPS.