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Differential associations of cognitive insight components with pretreatment characteristics in first-episode psychosis
Authors:  sar Gonzá  lez-Blanch,Mario Á  lvarez-Jimé  nez,Rosa Ayesa-Arriola,Obdulia Martí  nez-Garcí  a,Gema Pardo-Garcí  a,Vicent Balanzá  -Martí  nez,Paula Suá  rez-Pinilla,Benedicto Crespo-Facorro
Affiliation:1. Psychiatry Research Unit of Cantabria, IFIMAV, University Hospital “Marqués de Valdecilla”, Santander, Spain;2. Orygen Youth Health Research Center, Center for Youth Mental Health, University of Melbourne, Melbourne, Australia;3. CIBERSAM, Centro Investigación Biomédica en Red Salud Mental, Madrid, Spain;4. Section of Psychiatry and Psychological Medicine, Department of Medicine, University of Valencia Medical School, Valencia, Spain
Abstract:An increasing number of studies have focused on cognitive insight (i.e. awareness of one's own thinking) in psychotic disorders. However, little is known about the premorbid and pretreatment correlates of cognitive insight in the early course of psychosis. One hundred and three patients experiencing first-episode psychosis (FEP) were assessed shortly after treatment initiation for cognitive insight. Pretreatment and baseline clinical, functional and neurocognitive characteristics were examined. The self-reflectiveness dimension of cognitive insight was independently associated with clinical insight and executive functioning, whereas self-certainty was associated with premorbid IQ, premorbid academic adjustment and clinical insight. The amount of variance explained by the independent variables was small to moderate. Self-reflectiveness and self-certainty have differential pretreatment correlates in FEP and may reflect separate cognitive processes which require targeted interventions.
Keywords:First-episode psychosis   Schizophrenia   Insight   Neurocognition   Pre-morbid
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