| 支气管动脉灌注治疗中晚期肺癌40例疗效分析 |
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| 引用本文： | 侯文忠,于昭,邱伟江.支气管动脉灌注治疗中晚期肺癌40例疗效分析[J].实用医技杂志,2006,13(13). |
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| 作者姓名： | 侯文忠 于昭 邱伟江 |
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| 作者单位： | 梅州市人民医院,广东,梅州,514031 |
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| 摘 要： | 目的:评价支气管动脉灌注(bronchial arterial infusion,BAI)化疗药物治疗中晚期肺癌的疗效及安全性。方法:对40例中晚期肺癌患者行支气管动脉插管,通过支气管动脉灌注化疗药物。采用顺铂(DDP)50mg~60mg或卡铂(CBP)300mg~500mg、丝裂霉素(MMC)10mg和阿霉素(ADM)50mg三联药物,40例共行88次BAI治疗。结果:40例患者中完全缓解(CR)4例,部分缓解(PR)24例,稳定(SD)9例,进展(PD)3例,有效率(CR+PR)为70.0%,1a生存率为62.5%。鳞癌和富血供肺癌的BAI疗效分别优于腺癌和乏血供者(P<0.01)。结论:支气管动脉灌注治疗中晚期肺癌安全有效。
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| 关 键 词： | 肺癌 支气管动脉 治疗 |
The Evaluation of Bronchial Arterial Infusion Chemotherapy Effect on Mid-advanced Lung Cancer |
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| HOU Wen-zhong,YU Zhao,QIU Wei-jiang.The Evaluation of Bronchial Arterial Infusion Chemotherapy Effect on Mid-advanced Lung Cancer[J].Journal of Practical Medical Techniques,2006,13(13). |
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| Authors: | HOU Wen-zhong YU Zhao QIU Wei-jiang |
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| Abstract: | Objective clinical chemotherapy effect and safety of bronchial arterial infusion (BAI) in the mid-advanced lung cancer.Methods Forty patients of mid-advanced lung cancer confirmed by pathologhy received BAI treatment.In the combination of chemotherapy medicine,they were DDP (50 mg～60 mg) or CBP (300 mg～500 mg),MMC (10 mg) and ADM (50 mg).There were total 88 BAI in 40 patients.Results In 40 patients,there were 4 cases of complete response,24 cases of partial response,9 steady cases and 3 advanced cases.The curative results were 28 cases (70.0%) and one-year-survival rate was 62.5%.The chemotherapy effect of squamous carcinoma and sufficient-blood tumor was better than that of adenocarcinoma and insufficient-blood tumors,respectively (P<0.01).Conclusion BAI is an effective and safe method of treating the mid-advanced lung cancer. |
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| Keywords: | Lung tumor Arteries of bronchus Therapy |
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