曲安奈德在玻璃体切除手术中的应用研究

目的:研究曲安奈德(triamcinolone acetonide,TA)辅助玻璃体切除手术标记残余玻璃体皮质、玻璃体后皮质及视网膜前膜的应用,以及同对照组比较术后视力及眼压是否具有统计学意义。方法:对2004-01/2008-01行玻璃体切除术患者52例53眼,其中治疗组28眼术中玻璃体腔内注入TA,对照组25眼未用TA。术后平均随访6mo,观察两组视力及眼压的变化,分析其统计学意义。结果:治疗组和对照组术后2mo眼压:≥21mmHg分别是11%和9%,无统计学意义;两组手术前后视力的变化亦无统计学意义。结论:TA可以清晰标记残余玻璃体、玻璃体后皮质及视网膜前膜,提高手术效率,没有发现与TA有关的副作用。

Triamcinolone acetonide in vitreous surgery

AIM:To research triamcinolone acetonide(TA) assisted vitrectomy marked residual vitreous cortex, posterior vitreous cortex and epiretinal membrane, and whether there is statistical significance in visual acuity and intraocular pressure when compared with the control group. METHODS: From January 2004 to January 2008, 52 patients 53 eyes with vitrectomy, including treatment group 28 eyes with intravitreal injection of TA in the control group, 25 eyes did not use TA. The mean follow-up was 6 months, visual acuity and intraocular pressure changes were observed, and analyzed the statistical significance. RESULTS: The intraocular pressure in treatment group and control group after two months greater than 21mmHg were 11% and 9%, no statistical significance existed; There were no significant changes in visual acuity between the two groups before and after surgery.CONCLUSION: TA can clearly mark the residual vitreous, posterior vitreous cortex and epiretinal membranes, improve operation efficiency, no side effects are found related with TA.