X线照射后小鼠淋巴滤泡的动态变化

目的　探讨X线照射对小鼠月国窝淋巴结淋巴滤泡的影响。方法　采用组织学、免疫组织化学及三维重塑技术 ,观察小鼠全身X线照射后月国窝淋巴滤泡的变化。结果　小鼠全身X线照射后月国窝淋巴结重量迅速减小 ,淋巴细胞数量下降 ,淋巴滤泡被破坏。结论　X线照射可破坏淋巴滤泡 ,并经过一定时期可以重新聚集 ;再构筑的淋巴滤泡不是新产生的而是受损淋巴滤泡再生形成的

Dynamic changes of lymph follicles in mice after X-ray radiation

Objective To observe dynamic changes of lymph follicles in mouse popliteal lymph node after X ray radiation.Methods Through histological,immunocytochemical and 3 D reconstruction method,changes of lymph follicles in mouse popliteal lymph node after radiation were observed.Results After radiation the weight of lymph nodes were quickly reduced with lymphocytes decreasing and lymph follicles damaged.Conclusion X ray can damage lymph follicles,which can aggregate a little time later,but the reconstructed lymph follicles were not new ones,only recovered follicles from damaged ones.