原发性十二指肠恶性肿瘤53例临床分析

目的探讨原发性十二指肠恶性肿瘤的临床表现、病变部位、病理类型及辅助检查方法的选择。方法回顾性分析我院1998年1月~2004年12月确诊的53例原发性十二指肠恶性肿瘤患者的临床及病理资料。结果十二指肠恶性肿瘤患者的临床表现无特异性,可有腹痛、腹胀、黄疸、呕吐以及上消化道出血等,肿瘤好发于十二指肠降部,病理类型以腺癌为主,占90.5%。辅助检查以十二指肠镜检出率最高(95%),其他检查检出率依次为胃肠造影(92%)、胃镜(80%)、CT(76%)和B超(59%),结合上述多种检查可提高诊断率。结论提高原发性十二指肠肿瘤生存率的关键是早期诊断,对上述临床表现不能用常见疾病解释者应提高警惕性,结合十二指肠镜、GI、胃镜、CT、B超等多项辅助检查,达到早期诊断的目的。

Analysis of 53 cases of primary malignant tumor of the duodenum

Objective To study the clinical manifestations and location and pathological types of the primary malignant tumor of the duodenum and how to select the auxiliary examination.Methods The data of 53 cases of the primary malignant tumor of the duodenum were gathered and analyzed retrospectively from January,1998 to December,2004.Results Clinical manifestations were non-specific, which are abdominal pain,abdominal distention,jaundice,bowel obstruction and bleeding.The tumor was predilection in the descending part of the duodenum,The main pathological type is adenocarcinoma,90.5%.Diagnostic rates of image examination were EPCP 95%,GI 92%,gastroscope 80%,CT 76% and Ultrasound 59%,We should bind these auxiliary examinations exactly to raise the diagnostic rate.Conclusions Early diagnosis is the key point to increase the survival rate of the PMTD,so we should look out some clinical manifestation that could not be explained by the usual diseases and take multiple auxiliary examinations.