| 血浆中黄芩甙的HPLC测定方法 |
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| 引用本文： | 阴健,任天池,曹春林. 血浆中黄芩甙的HPLC测定方法[J]. 中国实验方剂学杂志, 1998, 4(1): 4-6 |
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| 作者姓名： | 阴健 任天池 曹春林 |
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| 作者单位： | 中国中医研究院中药研究所，北京中医药大学 |
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| 摘 要： | 采用ＨＰＬＣ法建立了家兔血浆中黄芩甙（ｂａｉｃａｌｉｎ）测定方法。用甲醇沉淀家兔血浆蛋白，氮气流将上清液吹干，以少量流动相溶解残渣，用ＨＰＬＣ方法测定。该方法可用于家兔静脉注射黄芩甙后血药浓度的测定。
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| 关 键 词： | 黄芩甙 HPLC法 药代动力学 |
| 收稿时间： | 1997-03-21 |
Determination of Baicalin in Rabbit Plasma by Reversed Phase HPLC |
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| Yin Jian,Ren Tianchi,Cao Chunlin. Determination of Baicalin in Rabbit Plasma by Reversed Phase HPLC[J]. China Journal of Experimental Traditional Medical Formulae, 1998, 4(1): 4-6 |
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| Authors: | Yin Jian Ren Tianchi Cao Chunlin |
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| Affiliation: | 1Institute of Chinese Materia Medica;China Academy of TCM,Beijing,100700;2Beijing University of TCM,Beijing,100029 |
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| Abstract: | The determination of baicalin in rabbit plasma was carried out by RP HPLC.The rabbit plasma was obtained by precipitating with methanol,evaporating the supernatant to dry with the nitrogen steam and dissolving the residual with small amount of the mobile phase.The average recovery was 98.80%. |
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| Keywords: | baicalin HPLC pharmacokinetics |
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