| 间质化疗临床应用研究进展 |
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| 引用本文： | 刘会波,王仁友,许健健,万德森. 间质化疗临床应用研究进展[J]. 中国肿瘤, 2005, 14(3): 174-177 |
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| 作者姓名： | 刘会波 王仁友 许健健 万德森 |
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| 作者单位： | 1. 合肥工业大学控释药物研究所,安徽,合肥,230009
2. 中山大学肿瘤医院,广东,广州,510060 |
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| 摘 要： | 抗肿瘤药缓释制剂植入肿瘤组织、瘤周组织的间质中或肿瘤切除后的瘤床,达到局部高药物浓度,降低系统毒副反应.杀死或抑制肿瘤病灶,减少、延迟局部复发或转移,改善预后,有着广阔发展前景.文章就间质化疗的概念、动物试验、常用缓释制剂及国内外临床应用作一综述.
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| 关 键 词： | 间质化疗 植入缓释制剂 肿瘤 药物疗法 |
| 文章编号： | 1004-0242(2005)03-0174-04 |
Progress on Clinical Application of Interstitial Chemotherapy |
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| LIU Hui-bo,WANG Ren-you,XU Jian-jian,et al.. Progress on Clinical Application of Interstitial Chemotherapy[J]. CHINA CANCER, 2005, 14(3): 174-177 |
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| Authors: | LIU Hui-bo WANG Ren-you XU Jian-jian et al. |
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| Abstract: | The sustained-release anticancer drug implantation can achieve high local concentration with reducing systematic toxicity by implanting sustained-release drug into tumor tissue or interstitial tissue.It can kill or inhibit tumor cells,reduce or delay the chance of local recurrence or metastasis, and improve prognosis with a broad prospect.The concept of interstitial chemotherapy,animal experiment,sustained-release agents and the clinical application are reviewed. |
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| Keywords: | interstitial chemotherapy sustained-release implant neoplasms drug therapy |
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