Pharmacology of anticoagulants used in the treatment of venous thromboembolism |
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| Authors: | Edith A. Nutescu Allison Burnett John Fanikos Sarah Spinler Ann Wittkowsky |
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| Affiliation: | 1.Department of Pharmacy Systems Outcomes and Policy and Center for Pharmacoepidemiology & Pharmacoeconomic Research,College of Pharmacy, University of Illinois at Chicago,Chicago,USA;2.Inpatient Antithrombosis Services, University of New Mexico Hospital,University of New Mexico College of Pharmacy,Albuquerque,USA;3.Brigham and Women’s Hospital,Massachusetts College of Pharmacy,Boston,USA;4.Philadelphia College of Pharmacy and Science,Philadelphia,USA;5.University of Washington School of Pharmacy,Seattle,USA |
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| Abstract: | Anticoagulant drugs are the foundation of therapy for patients with VTE. While effective therapeutic agents, anticoagulants can also result in hemorrhage and other side effects. Thus, anticoagulant therapy selection should be guided by the risks, benefits and pharmacologic characteristics of each agent for each patient. Safe use of anticoagulants requires not only an in-depth knowledge of their pharmacologic properties but also a comprehensive approach to patient management and education. This paper will summarize the key pharmacologic properties of the anticoagulant agents used in the treatment of patients with VTE. |
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