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自体造血干细胞移植治疗血管内大B细胞淋巴瘤1例
引用本文:李红华,王全顺,王书红,赵瑜,黄文荣,李向红,于力.自体造血干细胞移植治疗血管内大B细胞淋巴瘤1例[J].山东医药,2011,51(12):15-16,32.
作者姓名:李红华  王全顺  王书红  赵瑜  黄文荣  李向红  于力
作者单位:1. 中国人民解放军总医院,北京,100853
2. 北京市肿瘤医院
摘    要:目的探讨血管内大B细胞淋巴瘤(IVLBCL)的诊治。方法报告经自体造血干细胞移植治疗的1例女性IVLBCL患者的诊治经过,并复习相关文献。结果患者经肺活检及肾脏活检病理诊断为IVLBCL。经过R-CHOP方案6个疗程治疗后取得完全缓解,再经R-CHOPE方案1个疗程并动员采集自体外周血干细胞,行R-CBV方案为预处理方案的自体外周血干细胞移植,之后用利妥昔单抗巩固及维持治疗。术后随访25个月,患者持续完全缓解状态。结论本例IVLBCL患者采用R-CHOP联合自体外周血干细胞移植治疗及利妥昔单抗巩固维持取得满意疗效。

关 键 词:淋巴瘤  B细胞  诊断  造血干细胞移植

Treatment of intravascular large B-cell lymphoma with autologous stem-cell transplantation: a case report
LI Hong-hua,WANG Quan-shun,WANG Shu-hong,ZHAO Yu,HUANG Wen-rong,LI Xiang-hong,YU Li.Treatment of intravascular large B-cell lymphoma with autologous stem-cell transplantation: a case report[J].Shandong Medical Journal,2011,51(12):15-16,32.
Authors:LI Hong-hua  WANG Quan-shun  WANG Shu-hong  ZHAO Yu  HUANG Wen-rong  LI Xiang-hong  YU Li
Institution:LI Hong-hua1,WANG Quan-shun,WANG Shu-hong,ZHAO Yu,HUANG Wen-rong,LI Xiang-hong,YU Li (1 PLA General Hospital,Beijing 100853,P.R.China)
Abstract:Objective To study the diagnosis and treatment of a patient with intravascular large B-cell lymphoma(IVLBCL).Method To report a 49-year-old female case diagnosed IVLBCL and treated with autologous hematopoietic stem cell transplantation,and to review her relative clinical data.Results The patient was diagnosed IVLBCL through lung and kidney biopsy,and got complete remission after receiving 6 courses of rituximab-CHOP chemotherapy and then treated 1 course of rituximab-CHOPE followed by autologous peripheral...
Keywords:lymphoma  B cell  diagnosis  hematopoietic stem cell transplantation  
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