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| 消脱止-M治疗慢性下肢静脉功能不全的多中心临床观察 | |
| 引用本文： | 吴庆华,张福先,陈学明,庄百溪,刘建龙,李大军,韩延民,冯亚平,朱仁明,张童,田轩,李鹏,王海涛. 消脱止-M治疗慢性下肢静脉功能不全的多中心临床观察[J]. 心肺血管病杂志, 2010, 29(6): 474-476. DOI: 10.3969/j.issn.1007-5062.2010.06.011 |
| 作者姓名： | 吴庆华 张福先 陈学明 庄百溪 刘建龙 李大军 韩延民 冯亚平 朱仁明 张童 田轩 李鹏 王海涛 |
| 作者单位： | 1. 首都医科大学附属北京安贞医院-北京市心肺血管疾病研究所,北京,100029 2. 北京大学附属世纪坛医院 3. 首都医科大学附属北京友谊医院 4. 中国中医科学院西苑医院 5. 北京大学附属北京积水潭医院 6. 北京医院 |
| 摘 要： | 目的:观察消脱止-M对慢性下肢静脉功能不全(chronic venous insufficiency,CVI)的临床疗效和不良反应。方法:采用多中心开放、随机临床研究,对180例下肢静脉功能不全的患者予以口服消脱止-M,连续服用60d。4片/次,3次/d。儿童患者用量减半。观察服药后30d和60d临床症状改善程度。结果:口服消脱止-M,能够明显减轻患肢肿胀和疼痛(P0.001),明显加快患肢溃疡的愈合速度(P0.001)。用药60d时,临床症状改善更明显。未出现需要减量或停药的不良反应。结论:消脱止-M治疗慢性下肢静脉功能不全疗效显著、安全可靠。 |
| 关 键 词： | 消脱止-M 下肢静脉功能不全 血管疾病 草木犀流浸液 |
Multi-center clinical study of Setus-M in treatment for chronic venom insufficiency in lower limbs |
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| WU Qinghua,ZHANG Fuxian,CHEN Xueming,ZHUANG Baixi,LIU Jianlong,LI Dajun,HAN Yanming,FENG Yaping,ZHU Rerming,ZHANG Tong,TIAN Xuan,LI Peng,WANG Haitao. Multi-center clinical study of Setus-M in treatment for chronic venom insufficiency in lower limbs[J]. Journal of Cardiovascular and Pulmonary Diseases, 2010, 29(6): 474-476. DOI: 10.3969/j.issn.1007-5062.2010.06.011 | |
| Authors: | WU Qinghua ZHANG Fuxian CHEN Xueming ZHUANG Baixi LIU Jianlong LI Dajun HAN Yanming FENG Yaping ZHU Rerming ZHANG Tong TIAN Xuan LI Peng WANG Haitao |
| Affiliation: | Capital Medical University affiliated Beijing Anzhen Hospital,Beijing Institute of Heart,Lung and Blood Vessel Diseases,Beijing 100029,China |
| Abstract: | Objective：To study the efficacy and side reaction of Setus-M in the treatment for chronic venous insufficiency in lower limbs.Methods：An multi-center,open and randomized clinical research including 180 cases from 6 hospitals was carried out.Every patient was given 4 tablets of Setus-M once and three times per day.Symptomatic relief efficacy and side reaction were observed in 30 days and 60 days after druguse.Results：Symptoms of lower limb swelling,pain,ulcer were relieved much more obviously in 30 days and 60 days after drug-use（P 0.001）.With the treat-time prolonging that Setus-M was used in 60 days,the effectiveness ratio increased obviously.No side reaction caused the therapy interrupts.Conclusion：Setus-M is an effective and safe drug for the treatment of chronic venous insufficiency in lower limbs. |
| Keywords: | Setus-M Chronic venous insufficiency Blood vessel disease Melilotus Extract Ledeb |
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