加味桃红四物汤联合常规消肿疗法治疗足踝部骨折肿胀临床研究

目的：观察加味桃红四物汤联合常规消肿疗法治疗足踝部骨折肿胀的疗效。方法：选取118例气滞血瘀型足踝部骨折肿胀患者，按随机数字表法分为治疗组与对照组各59例。对照组给予常规消肿疗法治疗，治疗组给予加味桃红四物汤联合常规消肿疗法治疗。2组均连续治疗7 d。比较2组临床疗效及临床症状改善情况，比较2 组治疗前后中医证候积分、肿胀程度、疼痛程度[疼痛视觉模拟评分法（VAS） ]及血流变指标值（全血黏度、血浆比黏度） 的变化。结果：治疗组总有效率为98.31%，对照组为88.14%，2组比较，差异有统计学意义（P＜0.05）。治疗后，2组中医证候积分、肿胀程度、VAS评分均较治疗前下降（P＜0.05），治疗组上述3 项指标值均低于对照组（P＜0.05）。治疗后，治疗组肿胀减轻时间、疼痛消失时间均早于对照组（P＜0.05），踝关节背伸、踝关节屈曲度大于对照组（P＜0.05）。治疗后，2组全血黏度、血浆比黏度指标值均较治疗前下降（P＜0.05），治疗组全血黏度、血浆比黏度指标值均低于对照组（P＜0.05）。结论：加味桃红四物汤联合常规消肿疗法治疗气滞血瘀型足踝部骨折肿胀患者有利于改善血液黏稠度，促进血液循环恢复，缓解临床症状，减轻骨折处肿胀、疼痛，缩短肿胀、疼痛改善时间，加速关节功能恢复。

Clinical Study on Modified Taohong Siwu Decoction Combined with ConventionalDetumescence Therapy for Fracture Swelling of Foot and Ankle

Abstract： Objective： To observe the curative effect of Modified Taohong Siwu Decoction combinedwith conventional detumescence therapy for fracture swelling of foot and ankle. Methods ： A total of118 cases of patients with fracture swelling of foot and ankle of qi stagnation and blood stasis type wereselected and divided into the treatment group and the control group according to the random number tablemethod， with 59 cases in each group. The control group was treated with conventional detumescencetherapy， and the treatment group was treated with Modified Taohong Siwu Decoction combined withconventional detumescence therapy. Both groups were treated continuously for seven days. The clinicaleffects and improvement of clinical symptoms were compared between the two groups. The changes intraditional Chinese medicine syndrome scores， swelling degree， pain degree [Visual Analogue Scale forPain (VAS)]，and hemorheological index values (whole blood viscosity，and plasma specific viscosity) werecompared before and after treatment between the two groups. Results： The total effective rate was 98.31% in the treatment group， and 88.14% in the control group， the difference being significant (P＜ 0.05). After treatment， the traditional Chinese medicine syndrome scores， swelling degree， and VASscores in the two groups were decreased when compared with those before treatment (P＜0.05)，and thevalues of the above three indicators in the treatment group were lower than those in the control group (P＜0.05). After treatment， the swelling reduction time and pain disappearance time in the treatment groupwere earlier than those in the control group (P＜0.05)，and the ankle dorsiflexion and ankle flexion degreewere greater than those in the control group (P＜0.05). After treatment，the values of whole blood viscosityand plasma viscosity in the two groups were decreased when compared with those before treatment (P＜0.05)，and the values of whole blood viscosity and plasma viscosity in the treatment group were lower thanthose in the control group (P＜0.05). Conclusion： Modified Taohong Siwu Decoction combined withconventional detumescence therapy for patients with fracture swelling of foot and ankle of qi stagnation andblood stasis type is beneficial for improving blood viscosity， promoting blood circulation recovery，alleviating clinical symptoms， reducing swelling and pain at the fracture site， shortening the time forswelling and pain improvement，and accelerating joint function recovery.