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Prevalence,characteristics and risk factors of diabetic retinopathy in type 2 diabetes mellitus patients in Jordan: a cross-sectional study
Authors:Allaa Roto  Randa Farah  Mahmood Al-imam  Mohammed Q. Al-Sabbagh  Nakhleh Abu-Yaghi
Affiliation:1.Department of Special Surgery, Ophthalmology Division, School of Medicine, The University of Jordan, Amman, Jordan; 2.Department of Internal Medicine, School of Medicine, The University of Jordan, Amman, Jordan; 3.Department of Neurology, University of Kansas Medical Center, Kansas City, Kansas, USA
Abstract:ObjectivesTo measure the prevalence of diabetic retinopathy in patients with type 2 diabetes, to define their characteristics, and identify the associated risk factors.MethodsWe performed a cross sectional study of 1316 adult patients with type 2 diabetes mellitus who attended an ophthalmology clinic. Demographic, clinical, and laboratory data were analyzed. Diabetic retinopathy (DR) was diagnosed using a complete ophthalmic evaluation, including a fundic examination. Two regression models were constructed to identify the risk factors associated with DR and the parameters associated with the stage of retinopathy.ResultsMen accounted for 774 (58.8%) of the participants. The prevalence of DR was 28.2% (371 participants). DR was significantly more common in participants who were ≥60 years old, were women, had had diabetes for >10 years, were taking insulin, were not taking metformin, had a body mass index >30 kg/m2, were current smokers, or had a history of hypertension. Advanced stages of DR were more common in participants in the later stages of nephropathy and with albuminuria.ConclusionsPoor glycemic control, smoking, and advanced diabetic kidney disease are most closely associated with retinopathy. Further longitudinal studies are necessary to identify the mechanisms underlying these relationships and to guide community-based interventions.
Keywords:Diabetic retinopathy   type 2 diabetes mellitus   diabetic kidney disease   smoking   nephropathy   albuminuria   glycemic control
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