合理用药国际指标干预对我院呼吸内科和儿科门诊抗菌药物使用的影响

目的:探讨采取主动干预策略对我院呼吸内科和儿科门诊抗菌药物使用的影响。方法:通过前、后自身对照试验,对我院呼吸内科和儿科门诊抗菌药物合理用药的国际指标进行调研,采用主动干预医师处方行为策略进行干预,并分成干预前、1次干预后、2次干预后、3次干预后4个组别。数据用SPSS11.0软件进行统计、分析。结果:我院呼吸内科抗菌药物使用率、抗菌药物注射剂使用率分别从干预前的61.6%、19.2%下降至3次干预后的30.0%、14.0%(P<0.01);儿科两项指标分别从干预前的48.4%、25.6%下降至3次干预后的27.0%、14.0%(P<0.01);呼吸内科、儿科抗菌药物平均费用分别从干预前的28.2、31.5元降至3次干预后的11.8、12.3元;3次干预后抗菌药物联用现象均不存在;呼吸内科、儿科患者正确用药知晓率分别从90.0%、80.0%上升至干预后的100.0%、90.0%。结论:主动干预策略介入临床用药,对改善合理用药实践是有效和可行的。

Use of Antibiotics in Deparment of Respiratory Diseases and Pediatric Outpatient Department After Intervention on Rational Drug Use (RDU) with International RDU Index

OBJECTIVE： To explore the use of antibiotics in the department of respiratory diseases and pediatric outpatient department after the introduction of initiative intervention stragety on the rational use. METHODS： A field investigation was carried out on the international RDU index of antibiotics in the department of respiratory diseases and pediatric outpatient department by self--control test. Initiative intervention on physicians＇ prescribing practices was carried out at four stages： befter intervention, following first intervention, second intervention, and third intervention, respectively. Data statistics was analyzed by SPSS11.0 software. RESULTS： The percentages of patients treated with antibiotics and injcetable antibiotics in the department of respiratory diseases dropped from 61.6% and 19.2% before intervention to 30.0% and 14.0% after third intervention（P〈0.01）, and dropped from 48.4% and 25.6% before intervention to 27.0% and 14.0% after third intervention （p〈 0.01） in pediatric outpatient department. Antibiotic costs dropped from 28.2 yuan and 31.5 yuan before intervention to 11.8yuan and 12.3 yuan after third intervention in in the department of respiratory diseases and pediatric outpatient department,respectively.No combined use of antibitotics was noted in either department after the third intervention. Patientscognition rates toward correct medication increased from 90.0% and 80.0% to 100.0% and 90.0% in the two departments after the intervention. CONCLUSION： The initiative intervention strategies taken to improve rational drug use practice in the clinic is effective and feasible. KEY WORDS Antibiotics; International index of rational drug use; Intervention