集束化营养干预方案对食管癌同步放化疗患者生活质量和营养状况的影响

目的了解集束化营养干预疗法对食管癌同步放化疗患者生活质量和营养状况的影响程度。方法选取食管癌同步放化疗患者100例,应用随机、单盲、对照研究,采用随机数字表格法将患者分为研究组(采用集束化营养干预措施)和对照组(采用常规营养干预措施)各50例。食管癌放化疗结束后,比较2组患者的生活质量量表(EORTC QLQ-C3.0)及患者的体质量,血红蛋白(Hb)、血清白蛋白(ALB)含量及白细胞计数(WBC)等部分血液检查指标。结果入院时2组患者各项统计指标无统计学意义(P0.05);放化疗治疗结束后,研究组患者总体健康状况、体质量、Hb、ALB、WBC全部优于对照组,差异均具有统计学意义(P0.05)。结论集束化营养干预方案不仅可以明显提高食管癌同步放化疗患者的生活质量,而且可以改善患者的营养状况,值得在临床上进一步研究与应用。

Effect of cluster nutrition intervention on quality of life and nutritional status of esophageal cancer patients undergoing concurrent radiotherapy and chemotherapy

Objective To investigate the effect of nutritional intervention on the quality of life and nutritional status of esophageal cancer patients with concurrent radiotherapy and chemotherapy.Methods A total of 100 esophageal cancer patients with concurrent radiotherapy and chemotherapy in our hospital were equally divided into study group (cluster nutritional intervention) and control group (routine nutritional intervention) using random number table method.Quality of life scale (EORTC QLQ-C3.0) and body weight,the level of hemoglobin (HB),serum albumin (ALB) and white blood cell count (WBC) after radiotherapy and chemotherapy were compared.Results There was no significant difference on admission in different indicators (P ＞ 0.05).After radiotherapy and chemotherapy,overall health status,body weight,HB,ALB,WBC in the study group were all better than that of the control group (P ＜ 0.05).Conclusion Nutritional intervention can not only improve the quality of life of patients with esophageal cancer,but also enhance the nutritional status of patients,and it is worth of further study and application in clinical practice.