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Blue rubber-bled naevus syndrome: Report of a case with consumption coagulopathy complicated by manifest thrombosis |
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| Authors: | W. J. D. Hofhuis A. P. Oranje J. Bouquet M. Sinaasappel |
| Affiliation: | (1) Department of Paediatrics, Division of Haematology-Oncology, Erasmus University and University Hospital Rotterdam/Sophia Children's Hospital, Gordelweg 160, 3038 GE Rotterdam, The Netherlands;(2) Department of Dermatology and Venereology, Division of Paediatric Dermatology, Erasmus University and University Hospital Rotterdam/Sophia Children's Hospital, Gordelweg 160, 3038 GE Rotterdam, The Netherlands;(3) Department of Paediatrics, Division of Gastro-enterology, Erasmus University and University Hospital Rotterdam/Sophia Children's Hospital, Gordelweg 160, 3038 GE Rotterdam, The Netherlands |
| Abstract: | Blue rubber-bleb naevus (BRBN) syndrome is a rare disorder characterized by subcutaneous and gastrointestinal haemangiomas. The latter may lead to bleeding complications. A case is reported in which a process of chronic intravascular coagulation resulted in serious thrombotic complications. In the presence of a chronic consumption coagulopathy, it remains uncertain whether antiplatelet drugs are of prophylactic antithrombotic value. |
| Keywords: | Blue rubber-bleb naevus Consumption coagulopathy Thrombosis Aspirin |
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