腹腔镜胃癌根治术与开腹胃癌根治术对患者应激炎性因子影响的对比分析

目的探讨腹腔镜胃癌根治术与开腹胃癌根治术对患者应激炎性因子影响。方法胃癌并择期行根治性胃癌切除术治疗患者128例,随机分为腹腔镜组和开腹组各64例,腹腔镜组采取腹腔镜手术治疗,开腹组采取开腹手术治疗,对比两组患者手术及术后情况以及不同时间点应激炎性因子的变化。结果腹腔镜组患者的手术时间为（210.31±43.96）分钟,明显长于开腹组的（151.57±42.88）分钟;但腹腔镜组患者的切口长度为（5.85±1.08）cm,开腹组为（15.91±1.24）cm,腹腔镜组明显短于开腹组;术后各时点腹腔组患者的血清内皮素、一氧化氮、C-反应蛋白和白细胞介素-6等含量均明显低于开腹组,差异均有显著性。结论相比于开腹胃癌根治术,腹腔镜胃癌根治术具有创伤小、应激反应小,利于保持术后机体内环境的稳定以及促进患者术后康复的显著优势。

Comparison and analysis of laparoscopic and open radical gastrectomy for gastric cancer surgery in patients with stress-inflammatory factor

Objective To investigate comparison and analysis of laparoscopic and open radical gastrectomy for gastric cancer surgery in patients with stress-inflammatory factor. Method March 2009 to October 2013 in our hospital 128 cases of gastric cancer and gastric cancer undergoing radical resection were randomly divided into the laparoscopic group and open group,64 cases in each group,the laparoscopic group take laparoscopic surgery,laparotomy group taking laparotomy surgery and postoperative comparison of two groups of patients as well as changes at different time points of stress inflammatory factors. Result Laparoscopic surgery patients time was（210. 31 ± 43. 96） min,significantly longer than the laparotomy group（151. 57 ± 42. 88） min;,but the length of the incision laparoscopic group patients was（5.85 ±1.08） cm,laparotomy group（15. 91 ±1. 24） cm,the laparoscopic group was significantly shorter in the open group; abdominal surgery patients at each time point of NO,ET,IL-6 and CRP levels were significantly lower than the open and other groups,the differences were statistically significance. Conclusion Compared to open radical gastrectomy,Laparoscopic radical gastrectomy has a significant advantage in small trauma,small stress response,which will help maintain a stable internal environment and to promote postoperative patients＇ rehabilitation.