高危儿神经心理发育监测及早期干预治疗的临床观察

目的纵向了解高危儿的发育情况；探讨早期干预对高危儿在婴儿期神经心理发育的影响。方法选择2004年8月-2006年8月在我院出生和院外出生收入我科新生儿病室住院的高危儿184例为研究对象。出院时按家长的意愿分为干预组98例和对照组86例。对干预组患儿实施在医生指导下的家庭干预和医院综合康复治疗，定期随访，在婴儿6、12个月时采用0-6岁儿童心理精神发育量表对两组患儿进行神经心理发育的评估。对照组患儿进行常规育儿。结果干预组患儿在6个月及12个月时，大运动、精细运动、语言、适应能力、社交能力五大能区的发育商均较对照组高，两组比较差异具有统计学意义（P〈0．01）；干预组的后遗症发生率为2．04％（2／98），而对照组的后遗症发生率为19．77％（17／86），两组在预后方面差异有统计学意义（P〈0．01）。结论早期干预可促进高危儿的神经心理发育，预防和减轻高危儿的脑损伤后遗症，改善其预后。

Neuropsychology deveIopment monitoring and clinical observation of early intervendonal treatment of high-risk.infanls

Objective To investigate the developmental condition of high-risk infants and study the effect of early intervention on neuropsyehology development in infancy. Methods 184 high-risk infants in the ward of our department, who were born in our hospital or were received from other hospitals during the period from August in 2004 to August in 2006. were taken as the subject. They were divided into the intervention group with 98 cases and the control group with 86 eases at discharge according to the opinions of parents. The intervention group received family intervention under the doctors＇ guidance and comprehensive rehabilitation treatment of the hospital. And they were foUowed up regularly. The neuropsychology developmental condition of both groups was evaluated when they were 6 or 12 months old with Neuropsychology Development Scale, which is suitable for the children who are no more than 6 years old. Meanwhile, the control group was with conventional care. Results The development quotient of the intervention group in the five respects of intelligence.which includes gross motor,fine motor,language,adaptability and sociability was higher than that of the control group when they were 6 or 12 month, old. The difference between these two groups was of marked significance（ P 〈 0.01 ）. The incidence of sequela in the intervention group was 2.04% （2/98）, while the incidence in the control group was 19.77% （17/86）. And the prognosis difference between the two groups was very remarkable （ P 〈 0.01 ）. Conclusion Early intervention could improve the neuropsychology development of high-risk infants,prevent and reduce the sequela of brain injuries,improve the prognosis as well .