| 未分类湿疹患者血清白细胞介素12水平研究 |
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| 引用本文： | 尤艳明,李林峰. 未分类湿疹患者血清白细胞介素12水平研究[J]. 中国麻风皮肤病杂志, 2005, 21(11): 864-865 |
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| 作者姓名： | 尤艳明 李林峰 |
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| 作者单位： | 北京大学第三医院皮肤科,100083 |
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| 摘 要： | 目的：研究未分类湿疹患者血清IL-12水平。方法：应用ELISA方法测定了65例未分类湿疹患者血清白细胞介素12（IL-12）水平并与30例无过敏史健康对照者进行了比较。结果：（1）未分类湿疹患者血清IL-12水平高于对照组（P=0．04）。（2）急性期未分类湿疹患者血清IL-12水平和对照组相比无显著差异。（3）慢性期未分类湿疹患者血清IL-12水平高于对照组（P=0．004）。（4）急性期未分类湿疹患者血清IL-12水平和慢性期相比无显著差异：结论：在未分类湿疹的发病机制中，IL-12可能起一定的作用。
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| 关 键 词： | IL-12 未分类湿疹 血清白细胞介素 未分类 白细胞介素12 湿疹 患者 水 ELISA方法 对照组 |
| 收稿时间： | 2005-01-10 |
| 修稿时间： | 2005-01-10 |
The IL- 12 level in the sera of patients with unclassified eczema |
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| You Yanming,Li Linfeng. The IL- 12 level in the sera of patients with unclassified eczema[J]. China Journal of Leprosy and Skin Diseases, 2005, 21(11): 864-865 |
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| Authors: | You Yanming Li Linfeng |
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| Affiliation: | Department of Dermatology, Peking University Third Hospital, Beijing, 100083 |
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| Abstract: | Objective: To investigate the role of IL-12 in the pathogenesis of unclassified eczema (UE). Methods: The level of serum IL-12 in 65 patients with UE was detected by ELISA and compared with health controls. Results: (1) The level of serum IL-12 in UE was higher than that of control (P=0.04); (2) The level of serum IL-12 in acute UE was not different with that of control. (3) The level of serum IL-12 in chronic UE was higher than that of control (P=0.004). (4) The level of serum IL-12 in acute UE was not different with that of chronic UE. Conclusion: The results indicate that IL-12 may play an important role in UE. |
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| Keywords: | IL-12 unclassified eczema(UE) |
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