脉络膜血流灌注与儿童近视的相关性研究进展

近视是最常见的屈光不正类型。目前我国近视低龄化与快速增长特点明显，青少年儿童近视已成为全社会关注的公共卫生问题。视觉经验指导儿童屈光状态与正视化的发育。近视的发生与发展伴随着眼球结构改变，脉络膜呈现变薄趋势。脉络膜的厚度变化可能由血流灌注决定。脉络膜血流灌注下降可能导致巩膜缺血缺氧，缺氧诱导巩膜基质重塑和眼轴增长。本文就脉络膜血流与近视的相关性展开综述，提示关注脉络膜变化在近视防控中的意义。

Research progress on the correlation between choroidal blood flow perfusion and myopia in children

Myopia is the most common type of refractive error. At present, the characteristics of the low age and rapid growth of myopia in our country are obvious, and the myopia of adolescents and children has become a public health problem of concern to the whole society. Visual experience guides the development of children''s refractive state and emmetropization. The occurrence and development of myopia is accompanied by changes in the structure of the eyeball, and the choroid has a thinning trend. The thickness change of the choroid may be determined by blood flow perfusion. Decreased choroidal blood flow perfusion may lead to scleral ischemia and hypoxia, and hypoxia induces scleral matrix remodeling and axial length growth. This article reviews the relationship between choroidal blood flow and myopia, and suggests the significance of paying attention to choroidal changes in the prevention and control of myopia.