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Melissa Officinalis L. aqueous extract pretreatment decreases methotrexate-induced hepatotoxicity at lower dose and increases 99mTc-phytate liver uptake,as a probe of liver toxicity assessment,in rats |
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| Authors: | Shahani Somayeh Mehraban Nasrin Talebpour Amiri Fereshteh Abedi Seyed Mohammad Noaparast Zohreh Mohammadinia Salam |
| Institution: | 1.Department of Pharmacognosy and Biotechnology, Faculty of Pharmacy, Medicinal Plants Research Center, Mazandaran University of Medical Sciences, Sari, Iran ;2.Department of Radiopharmacy, Faculty of Pharmacy, Pharmaceutical Sciences Research Center, Mazandaran University of Medical Sciences, Sari, Iran ;3.Department of Anatomy, Faculty of Medicine, Molecular and Cell Biology Research Center, Mazandaran University of Medical Sciences, Sari, Iran ;4.Department of Radiology and Nuclear Medicine, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran ; |
| Abstract: | Annals of Nuclear Medicine - Hepatotoxicity remains amongst the restricting factors of Methotrexate (MTX)-associated cancer therapy, especially in high doses of chemo-drugs or prolonged treatment.... |
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