Kallmann综合征伴前列腺缺如一例并文献复习

<正>Kallmann综合征(kallmann syndrome,KS)是一种罕见的遗传性疾病，首次描述于1856年，后来由卡尔曼在1944年进行研究。主要表现为嗅觉-生殖器发育不良，与嗅球发育不全和性腺功能减退有关^[1]。男女发病率比例为5∶1，男性为1∶8000，女性为1∶40000^[2]。KS发病率低，临床上较少见，KS伴前列腺缺如临床更是罕见报道。笔者在浙江大学医学院附属第二医院进修期间于2021年11月23日收治1例KS伴前列腺缺如患者，现结合相关文献对其临床资料进行回顾性分析，报道如下。1临床资料

Kallmann syndrome with absence of the prostate: a case report and a literature review

Kallmann syndrome is a rare genetic disorder with high clinical and genetic heterogeneity. Absence of the prostate is rarely reported among the different clinical phenotypes of Kallmann syndrome. A case of Kallmann syndrome with absence of the prostate is reported. The clinical characteristics of the patient are analyzed and the literature is reviewed.