中西医结合治疗DVT过程中血浆CGRP水平

目的 :探讨急性深静脉血栓形成 (DVT)中西医结合治疗过程中血浆降钙素基因相关肽 (CGRP)水平及其临床意义。方法 :选择 5 0例急性深静脉血栓形成及 30例本病后遗症接受中西医结合治疗的病人 ,利用放射免疫分析动态观察其血浆CGRP水平。结果 :DVT患者中西医结合治疗后 6h血浆CGRP即明显升高 ,72h达高峰 ,与临床疗效最佳时间相符 ,而 30例后遗症病人则无明显变化。结论 :血浆CGRP水平可作为中西医结合临床治疗效果的一种检测指标 ,并可作为疾病进程的实验室指标。

Determination of Plasma Calcitonin Gene Related Peptide (CGRP) Levels in Patients with Deep Vein Thrombosis (DVT) During Treatment with Intergrated Chinese and Western Medicine

Objective To investigate the clinical significance of changes of plasma calcitonin gene related peptide (CGRP) levels during integrated Chinese and Western medical treatment in patients with deep vein thrombosis (DVT). Methods The plasma CGRP levels were determined dynamically with RIA during the course of integrated treatment in 50 patients with acute DVT and 30 patients with chronic DVT. Results In patients with acute DVT, the plasma CGRP levels were increased at 6h and reached peak values at 72h after starting the treatment, roughly correspoding to the time of most active thrombolysis. However, there were little change of CGRP levels in patients with chronic DVT. Conclusion Plasma CGRP levels might be taken as an indicator of the efficacy of integrated Chinese and western medical treatment for DVT.