胸部肿瘤术后心律失常原因探讨

报道６２例胸部肿瘤病人围手术期作血浆儿茶酚胺（ＣＡ）、动脉血氧分压（ＰａＯ２）及血清电解质测定和观察结果，以探讨术后心律失常的机理。血浆ＣＡ含量包括肾上腺素（Ｅ）和去甲肾上腺素（ＮＥ），均于术中开始升高，术后１～２天达高峰，较术前有明显差异（Ｐ＜０．００１）。ＰａＯ２术后１～４天较术前有明显降低（Ｐ＜０．００１）。除钾离子外，血清电解质术后均低于术前水平。结果表明：开胸术后心律失常与术后血浆ＣＡ升高、ＰａＯ２降低密切相关，与血清电解质关系有待进一步探讨。

A Study of the Cause of Postoperative Arrhythmias in Patients with Thoracic Cancer

The authors reported the results of determination of plasma catecholamine (CA) concentration, arterial oxygen tension(PaO2) and serum electrolytes (K , Na , Cl-,Mg ) during the perioperative period in 62 patients with thoracic cancer. Plasma adrenaline (AD) and noradrenaline (NA) concentrations started to increase during surgery , and reached their peak levels within first two postoperative days and were significantly higher than the preoperative values (P<0. 01). The values of PaO2 during the first four days were lower than that before operation (P<0. 001). Except for potassium, serum electrolytes values were lower in the first 3 postoperative days than preoperative ones.These results indicated: postoperative arrhythmia had a close relationship with the postoperative increment of plasma CA concentration and presence of hypoxemia.The relation between postoperative arrhythmia and changes of serum electrolytes requires further investigation.