芦荟对小鼠不同组织抗运动性氧化效果的比较研究

目的 比较芦荟对运动训练小鼠不同组织抗氧化效果的差别,为芦荟作为抗疲劳功能食品的开发利用提供实验依据。方法 建立小鼠游泳训练疲劳模型,测试小鼠不同组织在不同状态的总抗氧化能力(T-AOC)和丙二醛(MDA)含量。结果 与对照组比较,芦荟组小鼠心肌、肝脏、肾脏、骨骼肌和脑组织中T-AOC在安静状态、力竭游泳后即刻及恢复24h后均不同程度增加,而MDA均不同程度下降。结论 芦荟可不同程度提高运动小鼠各组织抗自由基氧化的功能,使小鼠运动能力明显提高。

Experimental Study of the Effect of Aloe on Metabolism of Free Radical and Ultrastructure of Liver in the Trained Mice

By building the Irained mice model, testing the aclivilie.s of SOD, GSH - Px and serum ALT , content of MDA, total antioxidation capacity (TAC) and liver index (LW/BW), and viewing the ultraslructure of mire' s liver, the effects of Aloe on metabolism of free radical and ultrastructure of liver were studied in Irained mice. The results indicate the activities of SOD and GSH - Px, LW/BW and TAG in most of Aloe groups are higher and the content ol MDA and ALT activities are lower in rest, immediately and 24-hour recovery after exhaustive exercise groups , comparing with relevant control groups. In rest slate. LW/BW and TAG of Aloe group obviously increase comparing with of control group(P <0. 05). All of targets are significant different between two groups in immediately after exhaustive exercise. After 24 - hour recovery, the SOD activities, LW/BW, TAC are obvious higher and content of MDA and activities of ALT are distinct lower in Aloe group than in control group. The changes of ultra-structure in liver also prove the effects of Aloe on protecting live from sports damage. Conclusion: Aloe could promote the mice capacity of anlioxidalion , reduce damage of ultrastructure of liver caused by exercise and increase exercise performance significantly in trained mice.