黄芪总皂甙对在体犬心功能的影响 |
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引用本文: | 雷春利,吕文伟,陈羽, 金辉.黄芪总皂甙对在体犬心功能的影响[J].吉林大学学报(医学版),1994(4). |
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作者姓名: | 雷春利 吕文伟 陈羽 金辉 |
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作者单位: | 吉林省计划生育科研所 |
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摘 要: | 结扎左冠状动脉前降支中点或最大斜角支根部,造成麻醉犬急性心肌梗塞模型,用RM一6000多道记录仪动态监测心功能和心电图,并进行实验性治疗。证实黄芪总皂甙能明显改善心梗大的心肌收缩性能,增加冠脉流量,对心功能有保护作用。
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关 键 词: | 黄茂/·药理学,心肌梗塞/病理生理学,心肌收缩,血流动力学,疾病模型,动物 |
Effects of Astragalus saponins on dog cardiac functions in vivo |
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Institution: | Central Laboratory of Physiology;Jiln Prouincial Instit of Birth control |
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Abstract: | Acute myocardial infarction models were reproduced in anesthetized dogs by lig-ating the
midportion of the left anterior decending coronary artery or the root portion of its majordiagonal
branch. The cardiac function paraneters and the electrocardiogram were monitored withaRM一
6000 type polygraph,amd experimental treatments were given, The results indicated
thatAstragalus saponis were able to improve the myocardial contractility significantly, atteruate
thecoronary blood flow and thus play a proltective role on the cardiac functions。 |
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Keywords: | astragalus membranaceus/pharmacology myocardial infarction/phys-iopathology myocardial contraction henodynamics disease models animal |
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