| 大孔树脂分离纯化中草药中皂苷类成分的研究进展 |
| |
| 引用本文： | 龚行楚,闫安忆,瞿海斌.大孔树脂分离纯化中草药中皂苷类成分的研究进展[J].世界科学技术-中医药现代化,2013,15(2):329-334. |
| |
| 作者姓名： | 龚行楚 闫安忆 瞿海斌 |
| |
| 作者单位： | 浙江大学药物信息学研究所,杭州,310058 |
| |
| 基金项目： | 浙江省科技厅公益技术研究社会发展项目（2011C23095）: 大孔树脂吸附分离过程在线分析技术研究，负责人：龚行楚；高等学校博士学科点专项科研基金（20110101120149）: 基于中药体系特点的树脂吸附过程在线分析技术研究，负责人：龚行楚。 |
| |
| 摘 要： | 介绍了国内外大孔吸附树脂分离纯化药材和方剂中皂苷类成分的研究现状,总结了大孔树脂精制皂苷类成分的主要影响要素和数学建模方法,归纳出适合皂苷分离的大孔树脂特点.大孔树脂吸附皂苷类成分具有分离效率高,产品纯度高等特点,通过加强吸附和解吸等过程机制的研究,优化工艺参数,并开发色谱工艺控制策略可以进一步提高树脂精制效率,稳定皂苷产品质量.
|
| 关 键 词： | 大孔树脂 吸附 皂苷 |
| 收稿时间： | 2012/8/12 0:00:00 |
| 修稿时间： | 2013/4/19 0:00:00 |
Development of Saponin Purification with Chromatography Process Using Macroporous Resins |
| |
| Gong Xingchu,Yan Anyi and Qu Haibin.Development of Saponin Purification with Chromatography Process Using Macroporous Resins[J].World Science and Technology-Modernization of Traditional Chinese Medicine,2013,15(2):329-334. |
| |
| Authors: | Gong Xingchu Yan Anyi and Qu Haibin |
| |
| Institution: | Pharmaceutical Informatics Institute, Zhejiang University, Hangzhou 310058, China |
| |
| Abstract: | This article was aimed to introduce researches on saponin purification with macroporous resin packed column chromatography both at home and abroad. Main influencing factors and mathematical modeling of chromatography process were discussed. Characteristics of macroporous resins which are recommended for saponin purification were summarized. Saponin purification with macroporous resin packed column chromatography is efficient in the obtaining of high purity saponin. Understanding of the mechanism of chromatography process, optimization of process parameters, and developing new chromatography process control strategy can be helpful to enhance separation efficiency and obtain saponins with stable quality. |
| |
| Keywords: | Macroporous resin adsorption saponin |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
| 点击此处可从《世界科学技术-中医药现代化》浏览原始摘要信息 |
| 点击此处可从《世界科学技术-中医药现代化》下载免费的PDF全文 |
