| RNA干扰沉默骨桥蛋白对大鼠移植肾小管上皮细胞向间充质转分化的作用 |
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| 引用本文： | 张 挺,徐东亮,周强平,鲁 佩,殷长军,张 炜,徐正铨,顾 民.RNA干扰沉默骨桥蛋白对大鼠移植肾小管上皮细胞向间充质转分化的作用[J].南京医科大学学报,2011(6):818-823. |
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| 作者姓名： | 张 挺 徐东亮 周强平 鲁 佩 殷长军 张 炜 徐正铨 顾 民 |
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| 作者单位： | 南京医科大学第一附属医院泌尿外科肾移植中心,江苏 南京 210029;南京医科大学第一附属医院泌尿外科肾移植中心,江苏 南京 210029;南京医科大学第一附属医院泌尿外科肾移植中心,江苏 南京 210029;南京医科大学第一附属医院泌尿外科肾移植中心,江苏 南京 210029;南京医科大学第一附属医院泌尿外科肾移植中心,江苏 南京 210029;南京医科大学第一附属医院泌尿外科肾移植中心,江苏 南京 210029;南京医科大学第一附属医院泌尿外科肾移植中心,江苏 南京 210029;南京医科大学第一附属医院泌尿外科肾移植中心,江苏 南京 210029 |
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| 摘 要： | 目的:探讨骨桥蛋白(osteopontin,OPN)的shRNA干扰质粒在大鼠慢性移植肾肾病(chronic allograft nephropathy,CAN)模型中对大鼠移植肾上皮细胞向间充质转分化(epithelial to mesenchymal transition,EMT)的作用,初步探讨OPN在慢性移植物...
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| 关 键 词： | 骨桥蛋白 上皮向间充质转分化 间质纤维化 慢性移植肾肾病 |
| 收稿时间： | 2010/12/22 0:00:00 |
Effect of silencing osteopontin by RNA interference upon EMT of tubular epithelial cells in rats with chronic allograft nephropathy |
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| ZHANG Ting,XU Dong-liang,ZHOU Qiang-ping,LU Pei,YIN Chang-jun,ZHANG Wei,XU Zheng-quan and GU Min.Effect of silencing osteopontin by RNA interference upon EMT of tubular epithelial cells in rats with chronic allograft nephropathy[J].Acta Universitatis Medicinalis Nanjing,2011(6):818-823. |
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| Authors: | ZHANG Ting XU Dong-liang ZHOU Qiang-ping LU Pei YIN Chang-jun ZHANG Wei XU Zheng-quan and GU Min |
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| Institution: | Department of Renal Transplantation,the First Affiliated Hospital of NJMU,Nanjing 210029,China;Department of Renal Transplantation,the First Affiliated Hospital of NJMU,Nanjing 210029,China;Department of Renal Transplantation,the First Affiliated Hospital of NJMU,Nanjing 210029,China;Department of Renal Transplantation,the First Affiliated Hospital of NJMU,Nanjing 210029,China;Department of Renal Transplantation,the First Affiliated Hospital of NJMU,Nanjing 210029,China;Department of Renal Transplantation,the First Affiliated Hospital of NJMU,Nanjing 210029,China;Department of Renal Transplantation,the First Affiliated Hospital of NJMU,Nanjing 210029,China;Department of Renal Transplantation,the First Affiliated Hospital of NJMU,Nanjing 210029,China |
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| Abstract: | |
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| Keywords: | osteopontin EMT interstitial fibrosis chronic allograft nephropathy |
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