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高血压病者血浆花生四烯酸的浓度变化及与血液流变学的关系
引用本文:邹宝明,鲍正毅,李俭春,江时森,骆合德. 高血压病者血浆花生四烯酸的浓度变化及与血液流变学的关系[J]. 中国微循环, 1995, 0(2)
作者姓名:邹宝明  鲍正毅  李俭春  江时森  骆合德
作者单位:中国人民解放军第105医院!安徽省合肥市230031(邹宝明,鲍正毅),中国人民解放军南京总医院(李俭春,江时森),中国人民解放军第98医院(骆合德)
摘    要:本文研究44例高血压病者血花生四稀酸含量变化及其与TXB_2和血液流变学方面的影响.结果:1.高血压病者血花生四稀酸和TXB_2浓度显著高于正常人(分别为P<0.01和P<0.05);2.血液流变学指标亦较正常人显著增高(P<0.05~P<0.001).随着血压降低,上述各项指标均下降.提示花生四稀酸通过影响血液流变学的变化在高血压病的发生和发展中起重要作用.

关 键 词:高血压  花生四稀酸  血栓素B_2  血液流变学

Changes of Plasma Arachidonic Acid Concentration in Hypertension and Its Relation to Hemorheology
Chinese PLA No. Hospital,Hefei.Zou Baoming,Bao Zenyi.Chinese PLA Nanjing General Hospital,Nanjing. Li Jianchun,Jiang Shisheng.Chinese PLA No Hospital,Luo Hede. Changes of Plasma Arachidonic Acid Concentration in Hypertension and Its Relation to Hemorheology[J]. Journal of Chinese Microcirculation, 1995, 0(2)
Authors:Chinese PLA No. Hospital  Hefei.Zou Baoming  Bao Zenyi.Chinese PLA Nanjing General Hospital  Nanjing. Li Jianchun  Jiang Shisheng.Chinese PLA No Hospital  Luo Hede
Affiliation:Chinese PLA No. 105 Hospital,Hefei.Zou Baoming,Bao Zenyi.Chinese PLA Nanjing General Hospital,Nanjing. Li Jianchun,Jiang Shisheng.Chinese PLA No 98 Hospital,Luo Hede
Abstract:The changes of plasma arachidonic acid concentration in 44 patients with hypertension and its effect on TXB_(2) and indices of blood rheology were studied. The results : 1. The plasma arachidonic acid and TXB_(2) concentration in patients with hypertension were significantly higher than those in normal persons (P< 0. 01 and P<0. 05. respectively). 2. Whole blood viscosity,plasma viscosity,HCT and plasma fibrinogen in patients with hypertension were significantly higher than those in normal persons(P<0.05,P<0. 001). With decrease of blood pressure ,all patients mentioned above were gradually reduced. This suggests that arachidonic acid may play an important role in both etiology and development of hypertension.
Keywords:Hypertension Arachidonic acid TXB2 Blood rheology
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