| 微电极引导的苍白球鼠损术对帕金森病患者认知功能的近期影响 |
| |
| 引用本文： | 李淑华,陈海波,刘宗惠,刘建杰,王新德,蔡晓杰,郝秋星,赵虎林,陈霖.微电极引导的苍白球鼠损术对帕金森病患者认知功能的近期影响[J].中国神经免疫学和神经病学杂志,2001,8(2):100-103. |
| |
| 作者姓名： | 李淑华 陈海波 刘宗惠 刘建杰 王新德 蔡晓杰 郝秋星 赵虎林 陈霖 |
| |
| 作者单位： | 1. 卫生部北京医院神经内科，帕金森病及锥体外系疾病诊疗中心，北京100730
2. 海军总医院神经外科，北京 100037 |
| |
| 摘 要： | 目的：了解微电极引导的腹侧苍白球毁损术（PVP）对帕金森病（PD）患者认知功能的影响，方法：对接受PVP治疗的20例PD患者手术前后进行认知功能检查，临床记忆量表、线方向判断测验、言主流畅性及简明精神状态量表检查。结果：左侧PVP患者术后临床记忆量表联想学习分测验成绩较术前显著减退（P＜0．05），其余记忆分测验、记忆商以及其他认知检查手术前后无显著改变（P＞0．05）；右侧PVP患者术后较术前各项检查成绩无明显改变（P＞0．05），手术后运动功能较术前显著改善（P＜0．05）。结论左侧苍白球参与了语言记忆，PVP对所检查的认知功能影响轻微。
|
| 关 键 词： | 帕金森病 苍白球毁损术 认知 微电极 |
| 文章编号： | 1006-2963（2001）02-100-04 |
| 修稿时间： | 2001年1月31日 |
Cognitive Outcome of Parkinsonian Patient Following Pallidotomy Induced by Micro-electrode |
| |
| LI Shu-hua,CHEN Hai-bo,Liu Zong-hui,Liu Jian-jie,WANG Xin-de,Cai Xiao-jie,Hao Qiu-xing,Zhao Hu-lin,Chen Lin.Cognitive Outcome of Parkinsonian Patient Following Pallidotomy Induced by Micro-electrode[J].Chinese Journal of Neuroimmunology and Neurology,2001,8(2):100-103. |
| |
| Authors: | LI Shu-hua CHEN Hai-bo Liu Zong-hui Liu Jian-jie WANG Xin-de Cai Xiao-jie Hao Qiu-xing Zhao Hu-lin Chen Lin |
| |
| Institution: | LI Shu-hua1,CHEN Hai-bo1,Liu Zong-hui2,Liu Jian-jie2,WANG Xin-de1,Cai Xiao-jie1,Hao Qiu-xing2,Zhao Hu-lin2,Chen Lin2 |
| |
| Abstract: | Objective To study the cognitive outcome of the patients with Parkinson disease (PD) following pallidotomy.Methods The cognitive changes following pallidotomy in 20 PD patients were studied by Clinical Memory Test(CMT), line orientation judgement, MMSE and verbal fluency tests.Results There were no significant cognitive changes before and after pallidotomy except the associative learning subtest of CMT(P< 0.05).The performance of associative learning subtest was significantly decreased after left pallidotomy. The motor impairment was significant.Conclusions It is suggested that the left pallidum might be related to the verbal memory. There were few cognitive changes following pallidotomy. |
| |
| Keywords: | Parkinson disease pallidotomy cognition |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
