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褶合光谱法测定中胃康胶囊中盐酸小檗碱的含量
引用本文:刘世军,金文祥,杨樊辉,赵丽娟,褚志杰.褶合光谱法测定中胃康胶囊中盐酸小檗碱的含量[J].药学实践杂志,2002,20(6):350-351.
作者姓名:刘世军  金文祥  杨樊辉  赵丽娟  褚志杰
作者单位:1. 武警山东省总队医院药剂科,济南,250101
2. 第二军医大学药学院药分教研室,上海,200433
摘    要:目的:不经分离直接测定中胃康胶囊中盐酸小檗碱的含量。方法:用TU-1901双光束紫外可见分光光度计采集吸收度信息,并通过数据转换将信息转到褶合光谱程序中,并由该程序单组分定量分析系统计算盐酸小檗碱的含量。结果:盐酸小檗碱的平均回收率和RSD分别为100.00%,0.03%。结论:本方法结果可靠、快速准确,可有效控制本品的质量。

关 键 词:中胃康胶囊  盐酸小檗碱  褶合光谱法  含量测定
文章编号:1006-0111(2002)06-0350-02
收稿时间:9/3/2002 12:00:00 AM
修稿时间:2002年9月3日

Determination of berberine hydrochloride in Zhongweikang capsules by convolution spectrometry method
LIU Shi-jun,JIN Wen-xiang,YANG Fan-hui,ZHAO Li-juan and CHU Zhi-jie.Determination of berberine hydrochloride in Zhongweikang capsules by convolution spectrometry method[J].The Journal of Pharmaceutical Practice,2002,20(6):350-351.
Authors:LIU Shi-jun  JIN Wen-xiang  YANG Fan-hui  ZHAO Li-juan and CHU Zhi-jie
Institution:Shandong General Troops Hospital of The Chinese People's Armed Police Forces, Jinan 250101, China;College of Pharmacy, The Second Militar-y Medical University; Shanghai 200433, China;Shandong General Troops Hospital of The Chinese People's Armed Police Forces, Jinan 250101, China;Shandong General Troops Hospital of The Chinese People's Armed Police Forces, Jinan 250101, China;Shandong General Troops Hospital of The Chinese People's Armed Police Forces, Jinan 250101, China
Abstract:OBJECTIVE: To determine berberine hydrochoride in Zhongweikan capsules without separation. METHODS: The absorption data was measured by the UV - VIS spectrophotometer, the convolution spectrometry method was used to calculate the concentration of berberine hydrochoride after absorption data transformation. RESULTS : The average recovery and RSD of berberine hydrocholoride were as follows; 100. 00% 0. 03% . CONCLUSION : Convolution spectrometry is reliable, accurate and suitable for the determination of the drug contents in hospital preparations.
Keywords:Zhongweikang capsule  berbeine hydrocholoride  convolution spectrometry method
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