中西医结合治疗镇静催眠药依赖性失眠症的临床观察

目的：研究戒断安神合剂和苯海拉明治疗镇静催眠药依赖性失眠症的临床疗效。方法：将70例患者随机分为治疗组和对照组,治疗组每日09：00和19：00时分别口服戒断安神合剂200ml,睡前30min口服苯海拉明25～50mg;对照组口服安神补心丸,每次15粒（2g）,日3次,睡前30min口服地西泮5～10mg。两组分别于治疗前后1w、2w、3w和4w用匹兹堡睡眠质量指数（PSQI）量表评定临床疗效。结果：治疗后1w、2w、3w和4w两组与治疗前比较PSQI分有显著性差异（P〈0．01）;治疗4w后两组间显效和总效率比较有显著性差异（P〈0．01）。结论：戒断安神合剂扣苯海拉明治疗镇静催眠药依赖性失眠症有较好疗效。

Dependent Insomnia of Sedative-hypnotics Treated with Integrated Traditional and Western Medicine

Objective：To study curative effect of dependent insomnia of sedative- hypnotics treated with abstinent mixtureof tranquilization and diphenhydramine. Methods：70 cases were randomly divided into 35 cases treated groups and 35 cases control groups, in treated groups take orally respectively abstinent mixtureof tranquilization about 200ml at 09：00,19：00and diphenhydramine before sleep 30min.In the control groups take orally 2 gram of anshen buxin pills,every time, th day was 3 times, 5-10 gram of diazepam before sleep 30min.Curative Effects were evaluated by means of scales for Pittsburgh sleep quality index（PSQI）in the two groups. Results：scores of PSQI after lw, 2w 3w and 4w significantly was better （P〈0.05） than that of before the treated in the two groups. Total：effective rate and significant rate showed significant difference after 4w in the two groups. Conclusion dependent insomnia of sedativehypnotics treated with abstinent mixtureof tranquilization and diphenhydramine was a better methods.