| He/icobacter py/ori infection in hemodialysis patients: Susceptibility to amoxicillin and clarithromycin |
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| 引用本文： | Selim Aydemir,Sedat Boyacioglu,Gurden Gur,Muge Demirbilek,Fusun Kamber Can,Murat Korkmaz,Ugur Yilmaz. He/icobacter py/ori infection in hemodialysis patients: Susceptibility to amoxicillin and clarithromycin[J]. World journal of gastroenterology : WJG, 2005, 0(6) |
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| 作者姓名： | Selim Aydemir Sedat Boyacioglu Gurden Gur Muge Demirbilek Fusun Kamber Can Murat Korkmaz Ugur Yilmaz |
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| 作者单位： | Department of Gastroenterology，Department of Gastroenterology，Department of Gastroenterology，Department of Clinical Microbiology，Department of Clinical Microbiology，Department of Gastroenterology，Department of Gastroenterology Zonguldak Karaelmas University Faculty of Medicine，67800，Zonguldak，Turkey，Baskent University Faculty of Medicine，06000，Ankara，Turkey，Baskent University Faculty of Medicine，06000，Ankara，Turkey，Baskent University Faculty of Medicine，06000，Ankara，Turkey，Baskent University Faculty of Medicine，06000，Ankara，Turkey，Baskent University Faculty of Medicine，06000，Ankara，Turkey，Baskent University Faculty of Medicine，06000，Ankara，Turkey |
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| 摘 要： | AIM: To evaluate susceptibility of Helicobacter pylori to amoxicillin and clarithromycin in end-stage renal disease (ESRD) patients and non-uremic controls. METHODS: The subjects with dyspeptic complaints were 33 ESRD patients and 46 age- and sex-matched non-uremic controls who exhibited H pylori on antral biopsy specimens. The two groups were age and sex matched. The H pylori strains' pattern of susceptibility to amoxicillin and clarithromycin was investigated with the agar dilution technique. RESULTS: None of the H pylori strains from either group showed resistance to amoxicillin with the agar dilution method. Twelve (36.4%) of the ESRD group strains and 7 (15.2%) of the control group strains showed resistance to clarithromycin, and this difference was statistically significant (P<0.05). CONCLUSION: Resistance to amoxicillin does not appear to be an important problem in H py/ori-infected ESRD and non-uremic patients in our region. In contrast, the rates of resistance to clarithromycin are high, particularly in the ESRD population.
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He/icobacter py/ori infection in hemodialysis patients: Susceptibility to amoxicillin and clarithromycin |
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| Selim Aydemir. He/icobacter py/ori infection in hemodialysis patients: Susceptibility to amoxicillin and clarithromycin[J]. World journal of gastroenterology : WJG, 2005, 0(6) |
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| Authors: | Selim Aydemir |
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| Affiliation: | Selim Aydemir,Department of Gastroenterology,Zonguldak Karaelmas University Faculty of Medicine,67800,Zonguldak,Turkey Sedat Boyacioglu,Gurden Gur,Murat Korkmaz,Ugur Yilmaz,Department of Gastroenterology,Baskent University Faculty of Medicine,06000,Ankara,Turkey Muge Demirbilek,Fusun Kamber Can,Department of Clinical Microbiology,Baskent University Faculty of Medicine,06000,Ankara,Turkey |
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| Abstract: | AIM: To evaluate susceptibility of Helicobacter pylori to amoxicillin and clarithromycin in end-stage renal disease (ESRD) patients and non-uremic controls. METHODS: The subjects with dyspeptic complaints were 33 ESRD patients and 46 age- and sex-matched non-uremic controls who exhibited H pylori on antral biopsy specimens. The two groups were age and sex matched. The H pylori strains' pattern of susceptibility to amoxicillin and clarithromycin was investigated with the agar dilution technique. RESULTS: None of the H pylori strains from either group showed resistance to amoxicillin with the agar dilution method. Twelve (36.4%) of the ESRD group strains and 7 (15.2%) of the control group strains showed resistance to clarithromycin, and this difference was statistically significant (P<0.05). CONCLUSION: Resistance to amoxicillin does not appear to be an important problem in H py/ori-infected ESRD and non-uremic patients in our region. In contrast, the rates of resistance to clarithromycin are high, particularly in the ESRD population. |
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| Keywords: | Helicobacter pylori Chronic renal failure Antibiotic resistance Clarithromycin Amoxicillin |
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