| 芳香中药精油成分在心血管疾病中的应用 |
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| 引用本文： | 罗晶,田鑫,刘波,王朝平,李林,杨明. 芳香中药精油成分在心血管疾病中的应用[J]. 中草药, 2020, 51(1): 245-255 |
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| 作者姓名： | 罗晶 田鑫 刘波 王朝平 李林 杨明 |
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| 作者单位： | 江西中医药大学药学院, 江西 南昌 330000;现代中药制剂教育部重点实验室, 江西 南昌 330000;创新药物与高效节能降耗制药设备国家重点实验室, 江西 南昌 330000,江西中医药大学临床医学院研究生院, 江西 南昌 330006,江西中医药大学药学院, 江西 南昌 330000,江西中医药大学药学院, 江西 南昌 330000,江西中医药大学附属医院, 江西 南昌 330006,江西中医药大学药学院, 江西 南昌 330000;现代中药制剂教育部重点实验室, 江西 南昌 330000;创新药物与高效节能降耗制药设备国家重点实验室, 江西 南昌 330000 |
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| 基金项目： | 国家重点研发计划（2018YFC1706404）；江西省中药学一流学科专项科研基金项目（JXSYLXK-ZHYAO09，JXSYLXK-ZHYAO082） |
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| 摘 要： | 芳香中药具有特殊的芳香气味,其中广泛存在着精油成分。精油成分可以通过清除氧自由基、舒张血管、改善脂质代谢、降低心率、抗血小板聚集等方式显著改善心血管疾病。总结目前已知的芳香中药精油成分在降低心血管疾病风险方面的作用及其机制。对芳香中药精油成分的研究有可能发现新的活性化合物,为开发治疗诸如动脉高血压、心绞痛、心力衰竭和心肌梗死等心血管疾病的新功能性产品提供思路。
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| 关 键 词： | 芳香中药 精油 心血管疾病 动脉高血压 心绞痛 心力衰竭 心肌梗死 |
| 收稿时间： | 2019-09-02 |
Application of essential oil components of aromatic Chinese materia medica in cardiovascular diseases |
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| LUO Jing,TIAN Xin,LIU Bo,WANG Chao-ping,LI Lin and YANG Ming. Application of essential oil components of aromatic Chinese materia medica in cardiovascular diseases[J]. Chinese Traditional and Herbal Drugs, 2020, 51(1): 245-255 |
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| Authors: | LUO Jing TIAN Xin LIU Bo WANG Chao-ping LI Lin YANG Ming |
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| Affiliation: | College of Pharmacy, Jiangxi University of Traditional Chinese Medicine, Nanchang 330000, China;Key Laboratory of Modern Traditional Chinese Medicine Preparation, Ministry of Education, Nanchang 330000, China;State Key Laboratory of Innovative Drugs and High Efficiency, Energy Saving and Consumption Reducing Pharmaceutical, Nanchang 330000, China,Clinical Medical College, Graduate School of Jiangxi University of Traditional Chinese Medicine, Nanchang 330006, China,College of Pharmacy, Jiangxi University of Traditional Chinese Medicine, Nanchang 330000, China,College of Pharmacy, Jiangxi University of Traditional Chinese Medicine, Nanchang 330000, China,Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine, Nanchang 330006, China and College of Pharmacy, Jiangxi University of Traditional Chinese Medicine, Nanchang 330000, China;Key Laboratory of Modern Traditional Chinese Medicine Preparation, Ministry of Education, Nanchang 330000, China;State Key Laboratory of Innovative Drugs and High Efficiency, Energy Saving and Consumption Reducing Pharmaceutical, Nanchang 330000, China |
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| Abstract: | Aromatic Chinese materia medica (CMM) have special aromatic odor, in which essential oils are widely present. It is reported that some essential oil components can significantly improve cardiovascular diseases by scavenging oxygen free radicals, relaxing blood vessels, improving lipid metabolism, reducing heart rate, and antiplatelet aggregation. Several mechanisms have been proposed for the role of essential oils in promoting cardiovascular health in aromatic CMM. The purpose of this review is to highlight and summarize the role of essential oils from aromatic CMM in reducing the risk of cardiovascular disease and their mechanisms. The research on essential oil components of aromatic CMM could discover new bioactive compounds and provide ideas for the development of new functional products for the treatment of cardiovascular diseases such as arterial hypertension, angina, heart failure, and myocardial infarction. |
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| Keywords: | aromatic Chinese materia medica essential oil cardiovascular disease arterial hypertension stenocardia cardiac failure myocardial infarction |
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