| 甘草及其有效成分的皮肤药理和临床应用 |
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| 引用本文： | 张明发,沈雅琴,张艳霞.甘草及其有效成分的皮肤药理和临床应用[J].现代药物与临床,2013,36(2):146-156. |
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| 作者姓名： | 张明发 沈雅琴 张艳霞 |
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| 作者单位： | 1.上海美优制药有限公司，上海 201422 2.青岛即墨市食品药品监督管理局，山东 即墨 266200 |
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| 摘 要： | 近年来临床上正在试用甘草及其有效成分的制剂治疗各种皮肤病，包括过敏性紫癜、银屑病、湿疹、玫瑰糠疹、荨麻疹、系统性红斑狼疮、小儿丘疹性肢端皮炎样皮疹、带状疱疹、扁平疣、斑秃、白癜风和皮肤色素沉着等。综述甘草提取物及其黄酮类化合物、甘草酸等对变态反应性皮肤病、皮肤肿瘤、病毒性皮肤病、色素沉着等皮肤病的药理作用和临床应用研究进展。
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| 关 键 词： | 甘草 甘草黄酮类 甘草酸 变应性皮肤病 病毒性皮肤病 毛发生成 黑素生成 |
| 收稿时间： | 2013/1/10 0:00:00 |
Dermatopharmacology and clinic application of Glycyrrhizae Radix et Rhizoma and its active components |
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| ZHANG Ming-f,SHEN Ya-qin,ZHANG Yan-xia.Dermatopharmacology and clinic application of Glycyrrhizae Radix et Rhizoma and its active components[J].Drugs & Clinic,2013,36(2):146-156. |
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| Authors: | ZHANG Ming-f SHEN Ya-qin ZHANG Yan-xia |
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| Institution: | 1.Shanghai Meiyou Pharmaceutical Co., Ltd., Shanghai 201422, China 2.Qingdao Jimo Food and Drug Administration, Jimo 266200, China |
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| Abstract: | In recent years, in clinic the preparations of Glycyrrhizae Radix et Rhizoma and its active components are being tried to treat various skin diseases, such as anaphylactoid purpura, psoriasis, eczema, pityriasis rosea, urticaria, systemic lupus erythematosus, eruption like papular acrodermatitis of childhood, herpes zoster, verruca plana, alopecia areata, leucoderma, skin pigmentation, etc. Research advances on the dermatopharmacology and clinic application of Glycyrrhizae Radix et Rhizoma as well as its flavonoids and glycyrrhizic acid in allergic dermatosis, tumor of skin, viral dermatosis, pigmentation, etc. are reviewed in this paper. |
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| Keywords: | Glycyrrhizae Radix et Rhizoma flavonoids glycyrrhizic acid allergic dermatosis viral dermatosis piliation melanogenesis |
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