| 薄层扫描法测定血尿康颗粒中盐酸水苏碱的含量 |
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| 引用本文： | 陈树明,孙冬梅. 薄层扫描法测定血尿康颗粒中盐酸水苏碱的含量[J]. 中国药房, 2005, 16(16): 1257-1258 |
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| 作者姓名： | 陈树明 孙冬梅 |
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| 作者单位： | 1. 广东东莞市人民医院,东莞市,523018
2. 广东省中医研究所,广州市,510095 |
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| 摘 要： | 目的:建立以薄层扫描法测定血尿康颗粒中盐酸水苏碱含量的方法。方法:采用硅胶G薄层板,展开剂为正丁醇-盐酸-醋酸乙酯(8∶3∶1),显色剂为稀碘化铋钾试液,测定波长为515nm,参比波长为700nm,狭缝大小为6.00mm×0.45mm。结果:盐酸水苏碱点样量在5.06μg～25.32μg范围内与斑点峰面积积分值呈良好的线性关系(r=0.9978),平均加样回收率为96.67%(RSD=2.01%)。结论:本方法简便、灵敏度高、重现性好,可用于血尿康颗粒的含量测定与质量控制。
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| 关 键 词： | 薄层扫描法 血尿康颗粒 盐酸水苏碱 含量 |
| 文章编号： | 1001-0408（2005）16-1257-02 |
| 收稿时间： | 2005-06-17 |
| 修稿时间： | 2005-06-17 |
Determination of Stachydrine Hydrochloride in Xueniaokang Granule by TLC Scanner |
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| Chen Shuming,Sun Dongmei. Determination of Stachydrine Hydrochloride in Xueniaokang Granule by TLC Scanner[J]. China Pharmacy, 2005, 16(16): 1257-1258 |
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| Authors: | Chen Shuming Sun Dongmei |
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| Abstract: | OBJECTIVE:To establish TLC scanner method for the determination of stachydrine hydrochloride in xueˉniaokang granule.METHODS:Silica gel G thin layer plate was adopted in the determination with n-butanol-hydrochloric acid-ethyl acetate(8∶3∶1)used as developer and thin potassium heptaiodobismuthate test solution used as color-developing agent,the detection wavelength was515nm,the reference wavelength was700nm and the slit size was6.00mm×0.45mm.RESULTS:Good linear correlation with the peak area score of spots achieved when the concentration range of stachydrine hydrochloride was within5.06μg～25.32μg(r=0.9978),the average recovery was96.67%(RSD=2.01%).CONCLUSION:The method was accurate,simple,reliable,sensitive and reproducible,and it can be used for the determination of xueniaokang granule and its quality control. |
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| Keywords: | TLC scanning method Xueniaokang granule Stachydrine hydrochloride Content |
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