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紫杉醇联合顺铂治疗晚期非小细胞肺癌的临床观察
引用本文:蒋秀贞,郭作超,史翠珍,林霞. 紫杉醇联合顺铂治疗晚期非小细胞肺癌的临床观察[J]. 现代肿瘤医学, 2007, 15(2): 208-209
作者姓名:蒋秀贞  郭作超  史翠珍  林霞
作者单位:山东省栖霞市人民医院肿瘤科,山东,栖霞,265300
摘    要:目的评价紫杉醇联合顺铂治疗非小细胞肺癌的临床疗效及毒性反应。方法紫杉醇150mg/m2静滴第1、8天,顺铂20mg静滴第1~5天,21天为1周期,治疗3个周期评价疗效。结果47例受治者,有效率为42.6%。毒副反应主要为恶心、呕吐、骨髓抑制。结论紫杉醇联合顺铂治疗非小细胞肺癌具有较好的疗效,毒副反应可以耐受。

关 键 词:肺癌  药物疗法  紫杉醇  顺铂
文章编号:23724943
修稿时间:2006-03-15

The effect of paclitaxel with cisplatin in the treatment of advanced non -small cell lung cancer
JIANG Xiu-zhen,GUO Zuo-chao,SHI Cui-zhen,LIN Xia. The effect of paclitaxel with cisplatin in the treatment of advanced non -small cell lung cancer[J]. Journal of Modern Oncology, 2007, 15(2): 208-209
Authors:JIANG Xiu-zhen  GUO Zuo-chao  SHI Cui-zhen  LIN Xia
Abstract:Objective: To investigate therapeatic efficacy and safety of paclitaxel with cisplatin on non-small cell lung cancer. Methods: Paclitaxel was administered at a dose of 150mg/m2 on day 1 and day 8, DDP 20mg from day 1 to day 5, cycles were repeated every 3 weeks, and 3 cycles were delivered for each patient. Results: Among 47 patients the overall response rate was 42.6%, the major side effect were gastrointestinal reation, arrest of bone marrow. Conclusion: Paclitaxel with cisplatin has better therapeutic efficacy on non-small cell lung cancer .
Keywords:lung cancer  drug therapy  paclitaxel  cisplatin
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