| 血液透析患者血清白蛋白水平与系统炎症反应的相关关系 |
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| 引用本文： | 姚英,刘惠兰,张香玲.血液透析患者血清白蛋白水平与系统炎症反应的相关关系[J].中国血液净化,2004,3(1):18-20. |
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| 作者姓名： | 姚英 刘惠兰 张香玲 |
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| 作者单位： | 100038,北京,首都医科大学附属复兴医院肾内科 |
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| 摘 要： | 目的研究血液透析患者血清白蛋白水平与系统炎症反应的关系.方法选择56例维持性血液透析患者,根据血清白蛋白(Albumin,Alb)水平分为两组:Alb<40g/L组和Alb≥40g/L组,比较两组白细胞介素6(interleukin-6,IL-6)、超敏C反应蛋白(high sensitive C-reactive protein,hs-CRP)和纤维蛋白原水平,并进行相关性分析.结果 Alb<40g/L组IL-6、hs-CRP和纤维蛋白原水平均较Alb≥40g/L组高,差异具有非常显著性(P<0.01).多元回归分析在矫正了年龄的影响后,IL-6是血液透析患者血清白蛋白水平的独立影响因素.结论血液透析患者血清白蛋白水平与系统炎症反应密切相关,提示血液透析患者营养不良的发生与存在的系统炎症反应有关.
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| 关 键 词： | 低蛋白血症 炎症 血液透析 |
| 修稿时间： | 2003年9月9日 |
Relationship between inflammation and serum albumin levels in hemodialysis patients |
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| YAO Ying,LIU Huilan,ZHANG Xiangling.Relationship between inflammation and serum albumin levels in hemodialysis patients[J].Chinese Journal of Blood Purification,2004,3(1):18-20. |
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| Authors: | YAO Ying LIU Huilan ZHANG Xiangling |
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| Institution: | YAO Ying,LIU Huilan,ZHANG Xiangling. Department o f Nephrology,Fuxing Hospital,Capital University of Medical Science,Beijing 10 0038,China |
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| Abstract: | Objective To evaluate the relationship between inf lammation and serum albumin levels in hemodialysis patients.Methods Serum albumin of 56 hemodialysis patients were measured and serum interleukin-6(IL-6),high sensitive C-reactive protein(hs-CRP)and fibr inogen concentration served as inflammation indexes were measured at the same ti me.Results Serum IL-6,hs-CRP and fibrinogen concentration were sign ificantly higher in patents with serum albumin level lower than 40g/L(P<0.01).In a stepwise multivariate regression analysis,adjusting for age,significant assoc iation was observed between serum albumin level and IL-6 concentration.Conclusion The presence of inflammation is associated with the s erum albumin level in hemodialysis patients. |
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| Keywords: | Hypoalbuminemia Inflammation Hemodialysis |
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