Lung function in adults following in utero and childhood exposure to arsenic in drinking water: preliminary findings |
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| Authors: | David C. Dauphiné Catterina Ferreccio Sandeep Guntur Yan Yuan S. Katharine Hammond John Balmes Allan H. Smith Craig Steinmaus |
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| Affiliation: | 1.Arsenic Health Effects Research Program, School of Public Health,University of California,Berkeley,USA;2.Pontificia Universidad Católica de Chile,Santiago,Chile;3.Veterans Affairs Medical Center,San Francisco,USA;4.Division of Environmental Health Sciences, School of Public Health,University of California,Berkeley,USA;5.Division of Occupational and Environmental Medicine,University of California,San Francisco,USA;6.Office of Environmental Health Hazard Assessment, California Environmental Protection Agency,Oakland,USA |
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| Abstract: | Purpose Evidence suggests that arsenic in drinking water causes non-malignant lung disease, but nearly all data concern exposed adults. The desert city of Antofagasta (population 257,976) in northern Chile had high concentrations of arsenic in drinking water (>800 μg/l) from 1958 until 1970, when a new treatment plant was installed. This scenario, with its large population, distinct period of high exposure, and accurate data on past exposure, is virtually unprecedented in environmental epidemiology. We conducted a pilot study on early-life arsenic exposure and long-term lung function. We present these preliminary findings because of the magnitude of the effects observed. |
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