| 调节源口服液对高脂大鼠血脂、红细胞膜流动性与脂质过氧化物的影响 |
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| 引用本文： | 许艳,王岩,朱翔,马波,陈丽娜,高佩琦. 调节源口服液对高脂大鼠血脂、红细胞膜流动性与脂质过氧化物的影响[J]. 中国血液流变学杂志, 1998, 0(4) |
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| 作者姓名： | 许艳 王岩 朱翔 马波 陈丽娜 高佩琦 |
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| 作者单位： | 哈尔滨医科大学生物物理教研室!哈尔滨1500860(许艳，王岩，朱翔，马波，陈丽娜)，哈尔滨医科大学生物物理教研室!哈尔滨15008(高佩琦) |
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| 摘 要： | 以外源性高脂血症大鼠模型研究调节源口服液对高脂血症大鼠血浆 中总胆固醇（ＴＣ）甘油三脂（ＴＧ），脂质过氧化物（ＬＰＯ）及红细胸膜流动性的影响。 并对其发生机制进行了初步探讨。研究表明：高脂血症大鼠血浆ＴＣ和ＬＰＯ水平 显著升高（Ｐ＜０．００１），膜流动性显著降低（Ｐ＜０．０２）。服用调节源口服液（主要成 份为黄芪多糖）１０日后，血浆 ＴＣ和 ＬＰＯ水平显著降低（Ｐ＜０．００１），膜流动性显 著升高（Ｐ＜０．０１）。其结果证实了调节源口服液在降低血脂，提高红细胞膜流动 性，抗氧化方面作用显著。
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| 关 键 词： | 调节源口服液 高脂血症 红细胞膜流动性 脂质过氧化物 |
EFFECTS OF THE ORAL SOLUTION OF TOGYRUN ON BLOOD LIPID MEBRANE FLUIDITY OF ERYTHROCYTES AND LIPID PEROXIDATION LEVEL |
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| Xu Yan. EFFECTS OF THE ORAL SOLUTION OF TOGYRUN ON BLOOD LIPID MEBRANE FLUIDITY OF ERYTHROCYTES AND LIPID PEROXIDATION LEVEL[J]. Chinese Journal of Hemorheology, 1998, 0(4) |
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| Authors: | Xu Yan |
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| Abstract: | The effects of the oral solution of ToGyRun on blood lipid, membrane fluidity of erythrocytes and lipid peroxidation were conducted in the rats with hyperlipidaemia. The experiment showed that in the rats with hyperlipidaemia, serum cholesteral concentration and lipid peroxidation significantly increased (P < 0. 001) while the membrane fluidity significantly lowered(P < 0. 02). After given the oral solution of ToGyRun was given for ten days, the serum cholesteral concentration and lipid peroxidation level significantly lowered (P <0. 001),while the membrane fluidity significantly increased (P <0.01). |
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| Keywords: | Oral solution of ToGyRun Hyperlipidaemia Membrane fluidity of erythrocy-tes Lipid peroxidation |
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