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血清中白介素-12与IgA肾病疗效分析
引用本文:张慧儒,薛兰芬,常丽丽. 血清中白介素-12与IgA肾病疗效分析[J]. 中国医药导刊, 2008, 10(4): 595-596
作者姓名:张慧儒  薛兰芬  常丽丽
作者单位:[1]石家庄市第一医院肾内科,石家庄050011 [2]石家庄市第一医院消化内科,石家庄050011
摘    要:目的:探讨血清中白介素-12(IL-12)与IgA肾病疗效关系。方法:经临床和肾活检确诊的IgAN患者60例,比较它们在不同程度尿蛋白排泄量和治疗前后血清中IL—12的变化。结果.IL-12在IgAN活动时升高,随着IgAN治疗好转IL-12降低,结论:因此IL-12可作为IgAN治疗是否好转的标志。

关 键 词:白介素12  IgA肾病  临床表现  病理

Analysis on the treatment Effect of Serum IL-12 on IgA Nephropathy
Zhang Hui-ru Xue Lan-fen Chang Li-lu. Analysis on the treatment Effect of Serum IL-12 on IgA Nephropathy[J]. Chinese Journal of Medicinal Guide, 2008, 10(4): 595-596
Authors:Zhang Hui-ru Xue Lan-fen Chang Li-lu
Affiliation:Zhang Hui-ru~1 Xue Lan-fen~1 Chang Li-lu~2 (1 Department of Renal Medicine,Shijiazhuang No.1 Hospital,Shijiazhuang 050011,China,2 Department of Digestive Medicine,China)
Abstract:Objective:To explore the correlation between serum IL-12 (IL-12) and IgA nephropathy.Methods:To compare the changes of serum IL-12 in urinary protein excretion before and after treatment through 60 cases of IgAN by clinical and renal biopsy confirmation.Results:IL-12 increased when IgAN is active.When IgAN recovered with the treatment,IL-12 went down. Conclusion:Therefore IL-12 canbe used as a sign if IgAN is recovered or not.
Keywords:IL-12  IgA Nephropathy  Clinical performance  Pathology  
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