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ABO血型不同供肝肝移植的临床应用
引用本文:吴凤东,吴风云,陈新国,臧运金. ABO血型不同供肝肝移植的临床应用[J]. 中国现代普通外科进展, 2009, 12(9): 752-754
作者姓名:吴凤东  吴风云  陈新国  臧运金
作者单位:1. 中国人民武装警察部队总医院,肝脏移植研究所,北京,100039
2. 武警医学院附属医院,普通外科,天津,300162
基金项目:武警总医院科研课题(wz2008011)
摘    要:目的:探讨供受体ABO血型不同肝移植的治疗及效果。方法:回顾性分析15例ABO血型不同肝移植临床资料。血型相容的6例采用常规治疗。血型不相容的9例均于术中显微镜下吻合肝动脉和胆道,术后采用四联免疫治疗方案及抗凝治疗,其中1例术前行血浆置换,5例术中切除脾脏。结果:血型相容的6例无并发症出现。血型不相容的9例中,4例患者顺利恢复,无并发症;其余5例中,3例出现急性排异反应,4例出现胆道非吻合口狭窄,3例死亡。结论:ABO血型不同但相容的供肝肝移植效果良好,血型不相容的供肝肝移植并发症多。当供体缺乏而受者病情不能等待时,可以选择性进行,但应该尽量减少并发症发生。

关 键 词:血型不合  ABO血型系统  肝移植

Clinical experience of ABO-diffferent liver transplantation
WU Feng-dong,WU Feng-yun,CHEN Xin-guo,ZANG Yun-jin Institute of Liver Transplantation,General Hospital of Chinese People' s Armed Police Forces. Clinical experience of ABO-diffferent liver transplantation[J]. Chinese Journal of Current Advances in General Surgery, 2009, 12(9): 752-754
Authors:WU Feng-dong  WU Feng-yun  CHEN Xin-guo  ZANG Yun-jin Institute of Liver Transplantation  General Hospital of Chinese People' s Armed Police Forces
Affiliation:Beijing 100039;China;Tianjin 300162;China
Abstract:Objective:To explore the treatment and effect of ABO-different orthotopic liver transplantation(OLT).Methods:Fifteen cases of ABO-different OLT were analyzed retrospectively.Six cases of ABO-different but compatible OLT were treated routinely.In 9 cases of ABO-incompatible OLT,plasma exchange was done in 1 case before operation,splenectomy was done in 5 cases during operation,the hepatic artery and biliary duct anastomosis were performed by the microvascular technique.The immuno suppressive protocol include...
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