Pipecuronium versus high dose vecuronium |
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Authors: | W. HARROP-GRIFFITHS N. FAUVEL M. PLUMLEY S. FELDMAN |
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Affiliation: | Department of Anaesthesia, St Mary's Hospital, London. |
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Abstract: | The onset time and tendency to cumulation of pipecuronium and high-dose vecuronium were studied during nitrous oxide anaesthesia supplemented with isoflurane. Pipecuronium 0.06 mg.kg-1 had a similar duration of action to vecuronium 0.015 mg.kg-1 (42 vs 49 min). Patients who received vecuronium had a shorter onset time of neuromuscular blockade (p less than 0.01). The use of pipecuronium was associated with marked cumulation. |
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Keywords: | Neuromuscular relaxants pipecuronium vecuronium Anaesthetics volatile isoflurane |
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