| HPLC法测定藿香正气软胶囊中的苍术素 |
| |
| 引用本文： | 刘志青,孙宝珍,朱小兰,商丹丹,石世学,赵晨.HPLC法测定藿香正气软胶囊中的苍术素[J].齐鲁药事,2010,29(3):146-148. |
| |
| 作者姓名： | 刘志青 孙宝珍 朱小兰 商丹丹 石世学 赵晨 |
| |
| 作者单位： | 1. 天津中新药业研究中心,天津,300457
2. 天津中新药业集团股份有限公司达仁堂制药厂,天津,300457 |
| |
| 摘 要： | 目的建立藿香正气软胶囊中苍术素的含量测定方法。方法用十八烷基硅烷键合硅胶柱;乙腈-水为流动相梯度洗脱;检测波长为336nm。结果在此条件下苍术素在0.01019~0.25475μg范围内线性关系良好,r=0.9999(n=6),平均回收率99.1%,RSD=1.96%。结论本方法简单可靠,可用于藿香正气软胶囊中苍术素含量的质量控制。
|
| 关 键 词： | 藿香正气软胶囊 苍术素 含量测定 |
Determination of atractylodin in Huoxiang Zhengqi Capsules by RP-HPLC |
| |
| LIU Zhi-qing,SUN Bao-zhen,ZHU Xiao-lan,SHANG Dan-dan,SHI Shi-xue,ZHAO Chen.Determination of atractylodin in Huoxiang Zhengqi Capsules by RP-HPLC[J].qilu pharmaceutical affairs,2010,29(3):146-148. |
| |
| Authors: | LIU Zhi-qing SUN Bao-zhen ZHU Xiao-lan SHANG Dan-dan SHI Shi-xue ZHAO Chen |
| |
| Institution: | LIU Zhi-qing,SUN Bao-zhen1,ZHU Xiao-lan,SHANG Dan-dan1,SHI Shi-xue,ZHAO Chen1(Tianjin Zhongxin Pharmaceutical R & D Center,Tianjin 300457,1.Tianjin Zhongxin Pharmaceutical Group Corporation LTD.Darentang Pharmaceutical Factory,Tianjin 300457) |
| |
| Abstract: | OBJECTIVE To establish a method for determination of atractylodin in Huoxiang Zhengqi Capsules by RP-HPLC.METHODS Separation was performed by HPLC on a RP-C18 analytical column with the mobile phase consisting of acetonitrile-water as gradient eluent,and the UV detection was set at 336 nm.RESULTS A good linear relationship for atractylodin was found in the range of 0.01019～0.25475μg（r=0.9999,n=6）.The mean recoveries for atractylidin was 99.1%（RSD=1.96%）.CONCLUSION The method is rapid and accurate for quality control of atractylodin in Huoxiang Zhengqi Capsules. |
| |
| Keywords: | Huoxiang Zhengqi Capsules atractylodin determination |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
