化积片治疗小儿厌食症的临床疗效观察

目的 探讨化积片治疗小儿厌食的疗效和安全性。方法 将50例小儿厌食的患儿随机分为试验组和对照组各25例，试验组服用化积片，一次3片，一日2次，对照组服用儿脾醒颗粒，3~5岁一次1.25g，一日3次，6~14岁一次2.5 g，一日3次，疗程4周。比较两组的食欲不振、体质量、中医证候疗效。结果 服药4周后，化积片治疗小儿厌食食欲不振疗效试验组总有效率92%；对照组2总有效率88%，两组比较差异无统计学意义；试验组治疗后平均体质量（18.37±1.72） kg，对照组（17.43±1.29） kg，两组间疗后比较，差异具有统计学意义（P<0.05）；试验组的中医证候疗效总有效率为96%、对照组为92%，试验组的愈显率为80%、对照组为68%，两组比较差异无统计学意义。结论 化积片治疗小儿厌食症在改善食欲不振症状，尤其改善患儿体质量方面，疗效确切，且用药安全性较好，无不良反应发生，值得在儿科消化科推广。

Effect of Huaji Tablets in the treatment of infantile anorexia

Objective To study effect and safety of Huaji Tablets in the treatment of infantile anorexia.Method 50 Cases of infantile anorexia were randomly divided into experimental group and control group (n=25). Experimental group take Huaji Tablets, 3 tablets per time, twice per day. Control group takes erpixing particles. Three to five years old:1.25 g/time, 3 times/day; Six to fourteen years old:2.5 g/time, 3 times/day, 4 weeks of treatment course. Comparison of two groups of loss of appetite, weight and syndromes curative effect.Result After 4 weeks of taking medicine, experimental group of Huaji Tablets in infantile anorexia show effective rate was 92%; For control group, effective rate was 88%, there was no significant difference between the two groups. Average weight for experimental group and control group was (18.37±1.72) kg and (17.43±1.29) kg respectively, comparison between the two groups after treatment, the difference was statistically significant (P< 0.05). Total effective rate and cure rate of syndromes curative effect for experimental group was 96% and 80%, for control group was 92% and 68%, there was no significant difference between the two groups.Conclusion Treatment of Huaji Tablets in infantile anorexia can improve the symptoms of anorexia, especially improve weight for infantile, it is effective and safe, no adverse effects were found, it is worth clinical promotion and application.