健脾固肠饮治疗脾虚湿热型溃疡性结肠炎随机平行对照研究

目的]观察健脾固肠饮治疗脾虚湿热型溃疡性结肠炎疗效。方法]使用随机平行对照方法，将78例门诊患者按就诊顺序编号随机分为两组，对照组38例柳氮磺胺吡啶片，1．0g／＆，3次／d。，治疗组40例健脾固肠饮（党参、白术、茯苓、木香、陈皮、半夏各12g，炒山药20g，炒薏苡仁10g，砂仁3g，白扁豆20g，黄连6g，炒吴莱萸3g，白及12g，葛根24g，甘草6g），1剂／d，水煎500mL，早晚口服。连续治疗2个月为1疗程。观测临床症状、大便性状、结肠黏膜、不良反应。治疗l疗程，判定疗效。结果]治疗组显效17例，有效20例，无效3例，总有效率92．50％。对照组显效9例，有效18例，无效13例，总有效率71．05％。治疗组疗效优于对照组（P〈0．05）。结论]健脾固肠饮治疗脾虚湿热型溃疡性结肠炎疗效满意，无副作用，值得推广。

A Parallelism Randomized Controlled Clincial Trial on Jianpiguchangyin in the Treatment of Ulcerous Colitis

Objective ] Observed Jianpiguchangyin treatment of ulcerative colitis. Methods ] Using randomized controlled methods, 78 outpatients were randomly divided into groups, the control group of 38 patients, sulfasalazine 1.0g, 3 times/day; treatment group of 40 used Jianpiguchangyin （Dangshen 12g, Baizhu 12g, Fuling 12g, Muxiang 12g, Chenpi 12g, Banxia 12g, Chaoshanyao 20g, Chaoyiyiren 10g, Sharen 3g, Baibiandou 20g, Huanglian 6g, Chaowuzhuyu 3g, Baiji 12g, Gegen 24g, Gancao 6g ）, 1 doses/day, decoction 500ml, twice on morning and evening. Two mouths of continuous treatment for a course of treatment. Observation of clinical symptoms, adverse reaction. Continuous 1 courses of treatment, the curative effect. Results ] The treatment group： 17 cases had marked effect, 20 cases were effective, 3 cases without effect; The control group： 9 cases had marked effect, 18 cases were effective, 13 cases without effect. The total efficiency of the observation group （ 92.50% ） higher than the control group （ 71.05% ）, with significant difference （ P〈0.05 ） . Conclusion ] Jianpiguchangyin is effective method to treat ulcerative colitis and no adverse reaction. It＇s worth promoting.