Effect of radiation on the heparanase mRNA expression in human colorectal carcinoma HT29 cells |
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引用本文: | 韩良辅,刘玉,石梅,孙朝阳. Effect of radiation on the heparanase mRNA expression in human colorectal carcinoma HT29 cells[J]. 中国临床康复, 2003, 7(6): 1002-1003 |
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作者姓名: | 韩良辅 刘玉 石梅 孙朝阳 |
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作者单位: | [1]DepartmentofObstetrics&Gynecology,XijingHospital,FourthMilitaryMedicalUniversity,XI‘an710032,ShannxiProvince,China [2]DepartmentofRadiotherapy,XijingHospital,FourthMilitaryMedicalUniversity,XI‘an710032,ShannxiProvince,China |
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摘 要: | AIM:To study the effect of exposure to 8MV X-ray irradiation on heparanase mRNA expression in human colorectal carcinoma HT29 cells.METHOD:In situ hybridization technique was used to study the expression of heparanase mRNA in HT29 cells.RESULTS:After exposure to the dose of 2 Gy,the heparanase mRNA expression in HT29 cells was significantly weakened.CONCLUSION:Radiation may inhibit the metastasis ability of HT29 cells.
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关 键 词: | 电离辐射 大肠癌 lrr29细胞 乙酰肝素酶 MRNA 表达 影响 研究 |
Effect of radiation on the heparanase mRNA expression in human colorectal carcinoma HT29 cells |
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Abstract: | AIM:To study the effect of exposure to 8MV X-ray irradiation on heparanase mRNA expression in human colorectal carcinoma HT29 cells.METHOD:In situ hybridization technique was used to study the expression of heparanase mRNA in HT29 cells.RESULTS:After exposure to the dose of 2 Gy,the heparanase mRNA expression in HT29 cells was significantly weakened.CONCLUSION:Radiation may inhibit the metastasis ability of HT29 cells. |
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