| 川芎嗪对缺氧-再给氧所致心肌细胞损伤的保护作用 |
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| 引用本文： | 冯婷,杜伟.川芎嗪对缺氧-再给氧所致心肌细胞损伤的保护作用[J].河南职工医学院学报,2005,17(4):198-199. |
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| 作者姓名： | 冯婷 杜伟 |
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| 作者单位： | 郑州大学护理学院,河南,郑州,450052;漯河市中心医院,河南,漯河,462000 |
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| 摘 要： | 目的 研究川芎嗪对冠心病保护的机制。方法 存建立心肌细胞缺氧再给氧损伤模型基础上，研究川芎嗪对细胞培养液中乳酸脱氧酶及心肌细胞中丙二醛含最的影响；同时，探讨其对心肌细胞凋亡率的影响。结果 川芎嗪可降低损伤心肌细胞培养液LDH及心肌细胞中MDA的含量。结论 川芎嗪对心脏缺血再灌注损伤具有一定的保护作用。
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| 关 键 词： | 川芎嗪 缺氧再给氧 心肌细胞 细胞凋亡 |
| 文章编号： | 1008-9276(2005)04-0198-02 |
| 收稿时间： | 03 20 2005 12:00AM |
| 修稿时间： | 2005年3月20日 |
Protective Effect of Ligustrazine on Hypoxia - reoxynation Induced Injury on Myocardial Cells |
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| FENG Ting,DU Wei.Protective Effect of Ligustrazine on Hypoxia - reoxynation Induced Injury on Myocardial Cells[J].Journal of Henan Medical College For Staff and Workers,2005,17(4):198-199. |
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| Authors: | FENG Ting DU Wei |
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| Institution: | 1. Nursing School of Zhengzhou University, Zhengzhou Henan 450052; 2. Luohe Centeral Hospital, Luohe Henan 462000, China |
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| Abstract: | Objective To investigate the protective mechanism of ligustrazine on heart.Methods After establishing hypoxia-reoxynation model on myocardial cells,the content of LDH,MDA and apoptosis rate were examined.Results The contents of LDH,MDA and myocardial cell's apoptosis rate were decreased.Conclusion Ligustrazine has protective effect on infarction-reperfusion injury. |
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| Keywords: | ligustrazine hypoxia-reoxynation myocardial cell apoptosis |
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